α,α-二乙氧基苯乙酮的合成新工艺  

Synthesis and Industrialization of α,α-Diethoxyacetophenone

作　　者：吴谦[1] 李双雯[1] 梁好[1] 刘畅[1] 蒋忠新[1] 江国防[1] 

机构地区：[1]湖南大学化学化工学院,湖南长沙410082

出　　处：《精细化工中间体》2009年第5期64-66,共3页Fine Chemical Intermediates

基　　金：国家自然科学基金资助项目(20502005);国家sit计划资助项目;湖南省科技计划项目(2009GK3187)

摘　　要：研究了二苯二硒与一种Lewis酸共催化苯乙酮与乙醇在过硫酸铵体系中合成α,α-二乙氧基苯乙酮(DEAP)的结果。经过对反应条件的优化,收率达96%。在实验室工艺的基础上,进行了反应、分离以及纯化工艺探索,实现了该工艺从实验室到工业化生产的应用。This paper reported a diphenyl diselenide and a Lewis acid co-catalyzed procedure for synthesizing α,α-diethoxyacetophenone （DEAP） from acetophenone, ethanol and ammonium persulfate. Modifications of the reaction conditions were studied in detail and DEAP was obtained under the optimum conditions in 96% yield. Based on lab technology, the industrialization of DEAP was achieved successfully.

关 键 词：α α-二乙氧基苯乙酮 催化 工业化 

分 类 号：TQ314.241[化学工程—高聚物工业]