72株阴沟肠杆菌的临床分布及其耐药性分析  

Clinical investigation and resistance analysis of 72 cases with Enterobacter cloacae

作　　者：王亨莉[1] 朱颖娴[1] 陈红涛[1] 杨冬铭[1] 

机构地区：[1]中山大学附属第五医院检验科,珠海519000

出　　处：《中国实用医药》2009年第30期56-57,共2页China Practical Medicine

摘　　要：目的分析阴沟肠杆菌在临床的感染和对常用抗生素的耐药性,以指导临床合理用药。方法对2007年7月至2009年7月从临床分离的阴沟肠杆菌的临床分布特点及耐药情况进行总结分析。结果72株阴沟肠杆菌标本主要源于痰液(32株,44.4%)和尿液(16株,22.2%);菌株分布于多个病区;阴沟肠杆菌对碳青酶烯类、头孢吡肟、派拉西林/他唑巴坦的敏感性较高。结论阴沟肠杆菌主要引起呼吸道、尿路感染,其耐药率较高,亚胺培南仍为治疗阴沟肠杆菌严重感染的首选用药。Objective To investigate the clinical distribution and antimicrobial resistance of infections caused by Enterobacter cloacae in our hospital, for guiding the clinical application of antibiotics reasonably. Methods Retrospective analysis of the drug resistance situation and specimen distribution was made to the Enterbacter cloacae got from 2007 to 2009. Results The rate of the isolate from sputum, and urine were 44. 4% （32 strains） and 22. 2% （16trains） respectively. All isolates of Enterbacter cloacae distributed in many departments, were more sensitive to carbapenem, cefepime, piperacillin/tazobactam. Conclusion Enterbacter cloacae mainly causes infection of respiratory tract and urinary tract in clinic which had higher drug-resistance. Imipenem remains to be the first choice to treat the severe infection which caused by Enterbacter cloacae.

关 键 词：阴沟肠杆菌 耐药性 医院感染 

分 类 号：R446.5[医药卫生—诊断学]