血清微量元素及生殖激素水平在男性不育症诊断中的意义  

Diagnostic significance of the serum trace elements and reproductive hormones in male infertility

作　　者：徐仙[1] 张文华[1] 薛玲芳[1] 曹缵孙[2] 

机构地区：[1]宁夏医学院附属医院,750004 [2]西安医科大学生殖内分泌研究室,710000

出　　处：《宁夏医学杂志》1998年第6期365-366,共2页Ningxia Medical Journal

摘　　要：目的探讨血清微量元素和生殖激素水平的测定在男性不育症诊断中的临床价值。方法应用原子吸收分光光度法和放免法对17例男性不育者和21例正常男子分别测定血清微量元素和生殖激素水平。结果不育组血清锌明显减低，而黄体生成素（LH）和泌乳素（PRL）则高于对照组（P＜0．05）；对照组锰含量与卵泡刺激素（FSH）、LH、PRL均呈负相关，而锌和铁与孕酮（P）正相关（P＜0．05），不育组锌与FSH、LH皆呈显著负相关（P＜0．01），铁与P亦呈负相关（P＜0．05）。结论同时检测血清锌、锰及FSH、LH、PRL水平可为男性不育症病因诊断及治疗提供有参考价值的实验依据。Objectives To investigate the clinic significance of the serum trace elements and reproductivc hormones in male infertility.Methods 17 infertile men and 21 matched normal men. Serum zinc (Zn), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni) and FSH, LH, PRL, E2, progesterone(P) were measured by atomic absorption spectrophotometry and RIA. Results There were signifi-cantly lower levels of serum Zn but higher LH and PRL in infertile group compared with the control group (P < 0. 05); a negative correlation in the control group between Mn and FSH, LH, PRL, however positive correlation between Zn, Fe and P(P < 0.05 ); a neg-ativc correlation existed in infertile group between both the Zn and FSH, LH(P < 0. 01 ) and the Fe and P(P <0. 05 ). Conclusions Mcasurement of the scrum Zn, Mn and FSH, LH, PRL simultaneously may serve as important evidencc of the etiologic diagnosis and therapy of male in fertility.

关 键 词：男性 微量元素 生殖激素 不育症 诊断 

分 类 号：R698.204[医药卫生—泌尿科学]