氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘的比较  

作　　者：艾美莲 花响岭 胡新和 

机构地区：[1]江西抚州市第一医院儿科,344000

出　　处：《当代医学》2009年第33期11-13,共3页Contemporary Medicine

摘　　要：目的比较氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘疗效及优缺点,探讨小儿哮喘治疗的最佳吸入方法。方法2007年1月～2009年1月我科收治的小儿支气管哮喘急性发作120例,随机分成两组,每组60例,在相同综合治疗的基础上,观察组用氧驱动雾化吸入布地萘德气雾剂0.5mg+复方异丙托溴铵溶液0.8ml+生理盐水1ml,每天2次。对照组采用空气压缩泵雾化吸入相同药物及次数,治疗4天后观察每组疗效,同时观察两组雾化吸入后血氧饱和度(SaO2)变化。结果吸入治疗4天后,观察组显效25例(41.7%),好转32例(53.3%),总有效57例(95.0%),无效3例(5.0%);对照组显效18例(30.0%),好转27例(45.0%),总有效45例(75.0%),无效15例(25.0%),观察组总有效率显著高于对照组(P<0.05)。观察组SaO2在雾化吸入前为(91.5±5.1)%,雾化吸入后为(96.3±3.9)%,雾化吸入后SaO2显著提高(P<0.05);对照组SaO2在雾化吸入前为(92.1±4.8)%,雾化吸入后为(92.3±4.2)%,雾化吸入前后差异无统计学意义(P>0.05)。结论氧驱动雾化和空气压缩泵雾化吸入均是治疗小儿哮喘急性发作的有效方法,但氧驱动雾化吸入治疗效果优于空气压缩泵雾化吸入,并可提高患者SaO2,是目前治疗小儿哮喘急性发作的首选方法。Objective To compare the effect, virtue and shortcoming of inhalation by oxygen jet nebulizer with air compress pump nebuliser in treating children asthma, so as to find the best inhalation method to treat children asthma. Methods 120 cases with acute bronchial asthma treated in our department from January 2007 to January 2009 were divided randomly into two groups, each group involved 60 cases.Based on general treatment,0.5mg Budesonide aerosol and 0.8ml complex Ipratropine solution with lml normal sodium were inhaled twice a day in observe group by using oxygen nebulizer, the same in control group by using air compress pump nebuliser. The effect of treatment after four days as well as oxygen saturation of blood after nebulization inhalation were observed in two groups）. Results After inhaling four days, 57（95.0%） cases were effective to treatment in observe group but 3（5.0%） cases invalid, including 25（41.7%） prominently effective cases and 32（53.3%） mend cases, however, only 45（75.0%） cases were effective to treatment in control group, including 18（30.0%） evidently effective cases and 27（45.0%） mend cases, 15（25.0%） cases were noneffective to treatment. The total effect rate of observe group Was remarkably higher than that of control group （P〈0.05）. The level of oxygen saturation of blood of observe group after nebulization inhalation, which was （96.3±3.9）%, was significantly higher than that before inhalation （P〈0.05）, which was （91.5±5.1） %. However, there was no significant difference of oxygen saturation of blood of control group after and before nebulization inhalation （P〉0.05）, which were （92.3±4.2）% and （92.1±4.8） %, respectively. Conclusion Although both of them were effective methods in treating children acute bronchial asthma, atomization inhaling by oxygen jet nebulizer, compared with air compress pump nebuliser, could improve the treatment effect and oxygen saturation of blood, which presently was the chief method in treating ac

关 键 词：氧驱动雾化器 空气压缩泵雾化器 哮喘 氧饱和度 

分 类 号：R725.6[医药卫生—儿科]