从中药对TLR-4的影响探讨冠心病PCI术后再狭窄的防治  

From the Traditional Chinese Medicine the Influence Initially Searches Coronary Disease PCI Technique After TLR-4 the Narrow Prevention

作　　者：唐虹[1] 李胜涛[1] 余昕[1] 吕品[1] 

机构地区：[1]成都中医药大学,四川成都610075

出　　处：《辽宁中医药大学学报》2009年第11期42-44,共3页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：冠心病是中老年人的常见病、多发病,亦是重大疾病,严重威胁着人民的健康和生命。而目前经皮冠状动脉介入治(PCI)术后冠脉再狭窄发生率高达20%～40%。有研究证实,炎症反应是PCI术后再狭窄的关键;而TLR-4是连接炎症反应与PCI术后再狭窄的桥梁。根据辨证论治的原则,中医从多角度出发在冠心病PCI术后再狭窄的防治中发挥着重要作用。Coronary atherosclerotic heart disease is common and frequently-occurring in the elderly, and also is a major disease ,a serious threat to the health and lives of the people. At present, the incidence rate of coronary artery restenosis is as high as 20% - 40% after percutaneous coronary intervention. Studies have confirmed that the inflammatory response is the key to coronary artery restenosis after PCI; and TLR-4 is a bridge connected the inflammatory response with restenosis after PCI. According to the principle of treatment based on syndrome differetiation,TCM plays an important role in the prevention and treatment of coronary artery restenosis after PCI from multi-angle.

关 键 词：冠心病 PCI术后 再狭窄 中药 

分 类 号：R541.4[医药卫生—心血管疾病]