碰撞池ICP-MS直接测定尿液中16个痕量元素的研究  

Direct determination of sixteen trace elements in urine by inductively coupled plasma mass spectrometry

作　　者：彭荣飞[1] 侯建荣[1] 黄聪[1] 卓召模[1] 贺小平[1] 邬志敏[1] 

机构地区：[1]广州市疾病预防控制中心,广州510080

出　　处：《中国卫生检验杂志》2009年第11期2475-2477,共3页Chinese Journal of Health Laboratory Technology

基　　金：广东省医学科研课题(A2008571);广州市医学科研课题(2007-YB-122;2007-YB-123)

摘　　要：目的：建立碰撞池ICP-MS直接测定尿液中16个痕量有毒元素的准确分析方法。方法：采用0.1%HNO3＋200μg/L Au对尿液稀释5倍后直接用ICP-MS进行分析,并采用碰撞/反应池技术来消除质谱干扰。结果：方法的检出限为0.01-0.25μg/L,精密度优于3.3%,回收率为94.0%-104%,标准参考物质的分析结果令人满意。结论：可用ICP-MS直接测定尿液中的16个痕量金属元素,整个方法具有简单、快速和准确的特点。Objective：To develop a accurate method for direct determination of sixteen trace elements in urine by collision cell inductively coupled plasma mass spectrometry.Methods：After dilution with 0.1%HNO3＋200 μg/L Au by a factor of 5,the urine was directly determined by inductively coupled plasma mass spectrometry using collision cell to eliminate mass spectroscopic interference.Results：The detections of limits were 0.01 0.25 μg/L,the RSD less than 3.3%,recoveries 94.0%-104% and the results of analyzing standard materiel were satisfactory.Conclusion：This method is simple,sensitive and accurate.It can be used for can direct determination of sixteen trace metal elements in urine.

关 键 词：ICP-MS 直接测定 尿液 痕量元素 

分 类 号：O657.63[理学—分析化学]