复方麝香注射液对老年脑梗死患者红细胞免疫功能调控的实验与临床观察  

The Experimental and Clinical Observation of Regulating of Red Cell Immunologic Function in Treating Elderly Cerebral Infarction Patients with Musk Injection Solution

作　　者：常国良 常盼盼[2] 赵小平 梁小乐 

机构地区：[1]长治市第二人民医院老年病研究所,山西长治046000 [2]中国医科大学,辽宁沈阳110001

出　　处：《中华中医药学刊》2009年第11期2409-2410,共2页Chinese Archives of Traditional Chinese Medicine

基　　金：长治市重点科技项目(200801002)

摘　　要：探索麝香注射液治疗老年脑梗死的红细胞免疫机理。方法:采用改良法红细胞免疫酵母菌花环试验方法为基础,将复方麝香注射液药物作为干预因素,根据加入或不加入复方麝香注射液分为药物干预的实验观察组、空白对照组和实验对照组,分别对其红细胞免疫指标RBC-C3bRR、RBC-ICR进行实验和对照分析。结果:无药物干预的空白对照组、实验对照组的RBC-C3bRR与药物干预的实验观察组RBC-C3bRR相比较,均有显著差异(P<0.05)。而两对照组相比较无显著差异(P>0.05)。3组RBC-ICR相比较均无统计学意义(P>0.05)。治疗前后RBC-C3bRR、RBC-ICR分别进行比较,P<0.05;均有显著差异,与实验结果一致。结论:麝香注射液对脑梗死患者红细胞免疫功能有明显的正向调节作用。Objective： To investigate the effects and mechanism of red cell immune system in treating elderly cerebral infarction patients with Musk injection solution（MIS） . Methods： MIS as intervention factor , based on the MIS is added or not, divided blood sample into three groups：the drug intervention＇s experimental group, blankness control group and experimental control group; The immune function of red cell was measured by improved yeast＇s garlands in 50 elderly patients with cerebral infarction（CI）. Results： The rat of red cell C3b receptor rosette of experimental group was significantly higher than that of blankness control group and experimental control group（ P 〈 0.05 ） ;But blankness control group com- pare with experimental control group wasn＇ t different （ P 〉 0.05 ）. The rate of immune complex rosette of three groups wasn＇t different（P 〉0.05）. Also before and after treatment were significantly different （P 〈 0.05） ,consistent with the experimental results. Conclusion： The decreasing function of reduced red cell immune system of cerebral infarction may be enhanced by MIS in cerebral infarction patients. K

关 键 词：老年人 脑梗死 红细胞免疫 C3B受体花环率 免疫复合物花环率 麝香注射液 

分 类 号：R285.5[医药卫生—中药学]