婴幼儿肺炎并心力衰竭血清心肌酶谱检测的临床意义  

The clinical significance of serum myocardial enzymes in children with pneumonia combined with heart failure

作　　者：牟静飞[1] 

机构地区：[1]广西壮族自治区妇幼保健院儿科,南宁530003

出　　处：《中国临床新医学》2009年第10期1069-1071,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨血清心肌酶谱在婴幼儿肺炎并心力心衰中的变化及临床意义。方法将收治的41例肺炎合并心力衰竭患儿为观察组,以同期住院的32例支气管肺炎患儿为对照组,对两组心肌酶谱进行回顾性分析。结果观察组心肌酶谱中肌酸激酶(CK)、肌酸激酶同功酶(CK-MB)、乳酸脱氢酶(LDH)、α-羟丁酸酶(α-HBDH)、谷草转氨酶(AST)均明显增高,与对照组比较有统计学显著意义(P<0.05或P<0.01);观察组恢复期AST较急性期显著降低(P<0.05),余心肌酶谱各指标呈下降趋势,但与急性期比较无统计学意义(P>0.05)。结论心肌酶谱可以反映婴幼儿肺炎合并心力衰竭时心肌受损的严重程度。CK-MB增高是判断心肌损害的关键指标,及时检查、积极治疗可以减少并发症的发生,提高抢救成功率,降低死亡率。Objective To explore the changes and clinical significance of serum myocardial enzymes in children with pneumonia combined with heart failure. Methods Forty-one children with pneumonia combined with heart failure who were treated in our hospital were selected as observation group. Thirty-two children with pneumonia in the same duration were selected as control group. Serum myocardial enzymes in the two groups were analyzed retrospectively. Results Compared with control group, the level of CK, CK-MB, LDH, α-HBDH and AST in observation group were significantly higher （ P 〈 0. 05 or P 〈 0. 01 ）. The level of AST in the restoration stage in observation group was significantly decreased than that in acute stage （ P 〈 0. 05 ）, and though the levels of other myocardial enzymes were also downtrend, the differences between acute stage and restoration stage were no statistical significance （ P 〉 0. 05 ）. Conclusion Myocardial enzymes can reflect the impaired degree of cardiac muscle in children with pneumonia combined with heart failure. The high level of CK-MB is a key index in the evaluation of ardiac damage. To examine in time and treat actively can reduce the happening of complication, elevate the achievement ratio of rescue and reduce the death rate.

关 键 词：婴幼儿肺炎 心力衰竭 心肌酶谱 

分 类 号：R563.1[医药卫生—呼吸系统]