Environmental Impacts on Spiking Properties in Hodgkin-Huxley Neuron with Direct Current Stimulus  

作　　者：袁常青 赵同军 展永 张素花 柳辉 张玉红 

机构地区：[1]Institute of Biophysics, Hebei University of Technology, Tianjin 300130

出　　处：《Chinese Physics Letters》2009年第11期239-241,共3页中国物理快报（英文版）

基　　金：Supported by the National Natural Science Foundation of China under Grant Nos 10775038 and 10747123, and the Hebei Provincial Natural Science Foundation under Grant Nos A2007000001 and C2007000026. We would like to thank Professor Yizhong Zhuo for helpful discussion.

摘　　要：Based on the well accepted Hodgkin-Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that,the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus.Based on the well accepted Hodgkin-Huxley neuron model, the neuronal intrinsic excitability is studied when the neuron is subject to varying environmental temperatures, the typical impact for its regulating ways. With computer simulation, it is found that altering environmental temperature can improve or inhibit the neuronal intrinsic excitability so as to influence the neuronal spiking properties. The impacts from environmental factors can be understood that,the neuronal spiking threshold is essentially influenced by the fluctuations in the environment. With the environmental temperature varying, burst spiking is realized for the neuronal membrane voltage because of the environment-dependent spiking threshold. This burst induced by changes in spiking threshold is different from that excited by input currents or other stimulus.

分 类 号：TP183[自动化与计算机技术—控制理论与控制工程] X820.3[自动化与计算机技术—控制科学与工程]