2种用药方案治疗妊娠期缺铁性贫血的成本-效果分析  

2 Therapeutic Schemes for Iron Deficiency Anemia in Pregnant Women:Cost-Effectiveness Analysis

作　　者：孙丽[1] 李雪莲[2] 林洁娜[1] 魏旭[1] 张鞠蕾[1] 吴胜元[1] 

机构地区：[1]广州医学院附属深圳沙井医院药剂科,深圳市518104 [2]广州医学院附属深圳沙井医院妇科,深圳市518104

出　　处：《中国药房》2009年第32期2485-2487,共3页China Pharmacy

摘　　要：目的:评价2种用药方案治疗妊娠期缺铁性贫血的临床疗效及经济学效果。方法:116例妊娠期缺铁性贫血患者随机分为A、B组,每组58例,A组给予复方硫酸亚铁叶酸片,B组给予益血生胶囊,疗程均为6周。观察2组疗效,并进行成本-效果分析。结果:A组与B组成本分别为561.416、525.632元,总有效率分别为93.1%、84.5%(P<0.05),成本-效果比分别为603.025、622.050,不良反应发生率分别为15.5%、13.8%(P>0.05)。A组相对于B组的增量成本-效果比为416.093。结论:复方硫酸亚铁叶酸片治疗妊娠期缺铁性贫血较佳。OBJECTIVE： To evaluate the curative efficacy and the economic effects of 2 therapeutic schemes in the treatment of iron deficiency anemia in pregnant women. METHODS： 116 pregnant women with iron deficiency anemia were randomly divided into 2 groups： Group A was assigned to receive compound ferrous sulfate and folic acid tablets（n = 58 cases）; Group B to receive Yixuesheng capsules（n = 58） . After treatment for 6 weeks, the curative efficacy was observed and the cost - effectiveness analysis was performed. RESULTS： For Group A vs. Group B, the total costs were 561.416 yuan vs. 525.632 yuan ; the overall effective rates were 93.1% vs. 84.5 % （P 〈 0.05） ; the cost - effectiveness ratios were 603.025 vs. 622.050; the incidences of adverse drug reactions were 15.5 % vs. 13.8% （P 〉 0.05） .The incremental cost - effectiveness of Group A was 416.093 as against Group B. CONCLUSION： Compound ferrous sulfate and folic acid tablets are optimal therapeutic scheme for iron deficiency anemia in pregnant women.

关 键 词：复方硫酸亚铁叶酸片 益血生胶囊 妊娠 缺铁性贫血 成本-效果分析 

分 类 号：R956[医药卫生—药学] R973.3