随机限食与重喂食小鼠的能量代谢和行为的可塑性  

Plasticity of Energy Metabolism and Behavior in Mice under A Random Food Restriction and Recovery

作　　者：赵志军[1,2] 王瑞瑞[1] 曹静[1] 

机构地区：[1]聊城大学农学院,山东聊城252059 [2]生态学与生物多样性山东省重点实验室

出　　处：《四川动物》2009年第6期862-866,共5页Sichuan Journal of Zoology

基　　金：国家自然基金资助项目(No.30800130);聊城大学博士科研启动基金资助项目(No.31805)

摘　　要：分别测定了随机限食和重喂食驯化的雌性KM小鼠的体重、摄食量、基础代谢率(BMR)、行为活动、身体脂肪和性腺重量。随机限食使摄食量增加、BMR和活动行为降低,生长发育迟缓,但对身体脂肪无显著影响。重喂食后上述指标均恢复到对照组水平,表现出显著的可塑性变化。结果表明,动物通过能量摄入和支出的权衡策略适应难以预测的食物资源变化,能量代谢和活动行为的可塑性调节在能量代谢的权衡策略中发挥重要作用。Body weight, food intake, basal metabolic rate （BMR）, behavior, body fat, and gonad mass were measured in female KM mice that acclimated to a random food restriction （FR） and recovery. Food intake increased significantly, but body weight, gonad mass, BMR and activity decreased in FR mice and there was no group difference in fat mass. That all the parameters above recovered after re-feeding indicated a significant plasticity. The present data suggested that an energy trade-off was employed to meet unpredictable variation of food availability. The plasticity of energy metabolism and behavior played an important role in the trade-off strategy.

关 键 词：限食 能量代谢 行为 重喂食 KM小鼠 可塑性 

分 类 号：Q41[生物学—生理学]