细菌性阴道病诊断试剂盒性能的比较研究  

Comparison of the Experimental Diagnostic Reagent Kits for Bacterial Vaginosis

作　　者：北京市生殖道感染综合干预课题组 董敬[1] 李丽[1] 石霞 万黎萍 张谦 安慧艳 吴尚纯[1] 

机构地区：[1]国家人口计生委科学技术研究所,北京100081 [2]北京市海淀区计划生育生殖健康技术服务中心 [3]北京市丰台区计划生育生殖健康技术服务中心

出　　处：《中国计划生育学杂志》2009年第11期679-681,共3页Chinese Journal of Family Planning

摘　　要：目的:比较细菌性阴道病(BV)速蓝快速诊断试剂盒和珠海浪峰快速诊断试剂盒的诊断价值。方法:选择600例疑为BV的妇女,均一次性取3份阴道分泌物标本,分别采用Amsel法、BV速蓝快速诊断试剂盒以及珠海浪峰快速诊断试剂盒进行BV检测,以Amsel法的检测结果为标准,比较两种试剂盒的检测结果与Amsel法的符合率。结果:600例阴道分泌物标本中的574例为有效标本,其中94例被Amsel法诊断为BV,BV速蓝试剂盒和珠海浪峰试剂盒与Amsel法的符合率分别为89.9%和59.4%,BV速蓝试剂盒的符合率明显高于珠海浪峰试剂盒(P<0.001);此外,珠海浪峰试剂盒(45.8%)的假阳性率明显高于BV速蓝试剂盒(7.9%)(P<0.001)。结论:BV速蓝快速诊断试剂盒快速、简便,假阳性率低,具有较好的临床应用前景。Objective： To compare two reagent kits for the diagnosis of bacterial vaginosis（BV）. Methods： Six hun-dred women with suspected BV were recruited. BV was detected at the same time by Arosel method, BVBLUE-A diagnostic reagent kit, and ZHUHAI diagnostic reagent kit respectively. The testing result of Amsel method was used for confirmed diagnosis of BV. The coincidence rates of the testing resuits of the two reagent kits with Amsel criteria were evaluated. Results ： Ninety-four of 574 validated samples were confirmed BV by Amsel method. The coincidence rates of BVBLUE-A diagnostic reagent kit and ZHUHAI diagnostic reagent kit were 89.9% and 59.4% respectively, showing that the former was significantly higher than the latter （P 〈 0.001）. In addition, the false positive rate of ZHUHAI diagnostic reagent kit （45.8%） was significantly higher than that of BVBLUE-A diagnostic reagent kit （7.9%）（P〈0.001）. Conclusion： BVBLUE-A diagnostic reagent kit should be a convenient tool with a lower false positive rate to use for diagnosing BV rapidly. It is enough to meet the clinical needs and have a better prospect for the clinical application.

关 键 词：细菌性阴道病 诊断试剂 AMSEL法 

分 类 号：R711.3[医药卫生—妇产科学]