基于CT图像的胸主动脉瘤模型数值模拟  

Numerical Simulation of Human Thoracic Aorta Based on CT Images

作　　者：付文宇[1] 乔爱科[2] 

机构地区：[1]北京工业大学机械工程与应用电子技术学院,北京100124 [2]北京工业大学生命科学与生物工程学院,北京100124

出　　处：《科技导报》2009年第20期27-31,共5页Science & Technology Review

基　　金：国家自然科学基金项目(10772010);北京市自然科学基金项目(3062003)

摘　　要：三维重建基于CT的胸主动脉瘤有限元模型并进行血流动力学数值模拟,为分析胸主动脉瘤的血流动力学机理及其临床治疗提供理论依据。依据临床胸主动脉瘤患者CT数据,结合MIMICS 11数字化影像处理软件,获取胸主动脉瘤的优化表面模型。随后导入ANSYS ICEMCFD 11.0进行胸主动脉瘤模型的有限元网格划分。最后在ANSYSCFX11.0中完成胸主动脉瘤的血流动力学分析。建立临床上适用于胸主动脉瘤患者血流动力学分析的有限元模型。获得了个性化胸主动脉瘤模型中血液流场的流线、速度矢量、血管壁面压力和血管壁面切应力的分布和变化。模型具有数字化、个性化特征,可用于胸主动脉瘤血液动力学计算和分析临床胸主动脉瘤患者动脉瘤的破裂机理。In order to provide a theoretical basis for the clinical treatment of thoracic aortic aneurysms, a 3D finite element model of thoracic aortic aneurysm is constructed, including ascending aorta, aortic arch, and descending aorta, with a fusiform aneurysm in descending aorta, together with three large branches （innominate artery, left common carotid artery, and left subclavian artery）. Numerical simulations of hemodynamics for this model is carried out. Based on the clinical patient-specific CT data of thoracic aortic aneurysm, image segmentation is carried out by MIMICS 11 and an optimized surface model of thoracic aortic aneurysm is constructed, which is imported into ANSYS ICEM CFD 11.0, where the volume meshes and boundary layer meshes are generated, and CFD analysis is performed. Numerical simulation is performed using a finite volume method. A finite element model for hemodynamics analysis of patient-specific thoracic aortic aneurysm is built. Distribution and changes of streamlines, velocity vector, pressure and wall shear stress are obtained for the patient-specific model. Such models with digital and patient-specific features can be applied to hemodynamic analysis of thoracic aortic aneurysm. Rupture mechanism of thoracic aortic aneurysms in a patient can be analyzed based on this kind of models.

关 键 词：胸主动脉瘤 CT图像 有限元模型 三维重建 壁面切应力 

分 类 号：R816.2[医药卫生—放射医学] R543[医药卫生—临床医学]