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作 者:林朝斌[1] 陈伟芳[1] 吴晓民[1] 庄国斌[1] 蔡卫国[1]
机构地区:[1]福建医科大学附属泉州第一医院眼科,泉州362000
出 处:《中国实用眼科杂志》2009年第10期1188-1190,共3页Chinese Journal of Practical Ophthalmology
摘 要:目的 观察青光眼滤过手术后早期包裹囊状泡进行针刺分离和泡内注射干扰素α-2b的疗效.方法 对21例(21只眼)早期(术后8~30d)的包裹囊状泡应用干扰素α-2b行滤过泡针刺分离和泡内注射1~5次不等,随访6个月,观察其治疗前、后眼压及滤过泡形态的变化.结果 治疗前眼压平均为(25.82±4.65)mmHg,治疗后为(15.20±5.43)mmHg,治疗前、后眼压差异有统计学意义(t=6.86;P<0.01).随访1、3、6个月后平均眼压分别为(14.66±4.36)、(13.97±2.69)、(14.98±4.61)mmHg,功能滤过泡形成率80.95%(17/21),条件成功率90.48%(19/21).随访6个月后平均眼压与治疗前的平均眼压之间差异有统计学意义(t=7.59;P<0.01).结论 应用干扰素a-2b对早期包裹囊状泡行针刺分离和泡内注射治疗可挽救一些频临失败的滤过泡,提高率过性手术的成功率,有较好地疗效,并发症少.Objective To observe the curative effect of acupuncture separation combined with injection of IFN a-2b for the treatment of the early Tenon' s capsule cysts after glaucoma filtration surgery.Methods Twenty-one cases with early Tenon's capsule cysts (8 to 30 days) were treated with acupuncture separation combined with injection of IFN a-2b once to five times.All patients were followed up for 6 months, to observe the variation of lOP and filtering blebs' form before and after the treatment.Results Before the treatment, the average IOP was (25.82±4.65)mmHg, and that was ( 15.20± 5.43)mmHg after the treatment.The difference was statistically significant ( t=6.86, P〈0.01 ).The average IOP was ( 14.66±4.36)mmHg after one month, and that was (13.97±2.69)mmHg after three months.After followed up for 6 months, the average IOP was 14.98±4.61mmHg, the rate of functional filtering blebs was 80.95% ( 17 in 21 eyes), and the rate of conditional success was 90.48% (19 in 21 eyes).The difference of the average lOP before the treatment and 6 months' follow up after the treatment was statistically significant (t=7.59, P〈0.01 ).Conclusions Acupuncture separation combined with injection of IFN a-2b is an effective procudure to treat the early Tenon's capsule cysts, it can retrieve some nearly failed filtering blebs, and improve the success rate of filtering surgery with few concurrent diseases.
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