血清和腹水采集间隔时间对血清-腹水白蛋白梯度和腹水／血清肿瘤学标志物比值鉴别腹水性质的影响  

Effect of sampleing time intervals on differential diagnosis of ascitic fluid

作　　者：张正荣[1] 胡娟[2] 邓彬[3] 丁岩冰[3] 

机构地区：[1]江苏省扬州市第一人民医院肿瘤科,225001 [2]江苏省扬州市第一人民医院检验科,225001 [3]江苏省扬州市第一人民医院消化科,225001

出　　处：《临床内科杂志》2009年第11期776-778,共3页Journal of Clinical Internal Medicine

摘　　要：目的研究血清和腹水采集间隔时间对腹水性质鉴别诊断的影响。方法采用血清-腹水白蛋白梯度（SAAG）和腹水／血清肿瘤学标志物（F／S比值）两种腹水分类标准，观察两种血清和腹水采集间隔时间（≤2h和〉2h）对上述两种腹水分类标准的结果分析有无影响。结果腹水患者105例，间隔时间≤2h时检测血清-腹水白蛋白梯度，其中54例SAAG≥g/L，51例SAAG〈11g／L；间隔时间〉2h时，50例SAAG≥11g／L，55例SAAG〈11g／L，两者之间比较无显著性差异（P〉0．05）；间隔时间≤2h时检测F／S比值，30例F／S≥1．2，75例F／S〈1．2，间隔时间〉2h时，33例F／S≥1．2，72例F／S〈1．2，两者比较也无显著性差异（P〉0．05）。结论血清和腹水采集间隔时间对按上述两种标准进行腹水性质分类并无明显影响。Objective To evaluate the effect of the time interval between ascitic fluid and serum samples on the interpretation of results. Method We examined SAAG and fluid/serum ratio of tumor marker （F/S） ratio from different sampling time intervals（ ≤2 h and 〉2 h） to identify if there is difference. Results Of 105 patients with ascitic fluids ,samples of serum and ascitic fluid were collected at two sampling time intervals（ ≤2 h and 〉2 h） ,SAAG was ≥11 g/L in 54 cases and 〈 11 g/L in 51 case,at the sampling time interval of less than 2 hours, SAAG was ≥ 11 g/L in 50 cases and 〈 11 g/L in 55 case at the interval of more than 2 hours,. There is no significant difference （ P 〉 O. 05 ） ; F/S was ≥ 1.2 in 30cases, and 〈 1. 2 in 75 at the sampling time interval of less than 2 hours, F/S was ≥ 1.2 in 33cases,and 〈 1.2 in 72 at the sampling time interval of more than 2 hours, There is no significant difference （ P 〉 0.05 ）. Conclusion Different sampling time intervals of serum and ascitic fluid does not effect the results of SAAG and F/S.

关 键 词：腹水 标本采集间隔时间 血清-腹水白蛋白梯度 腹水/血清肿瘤学标志物 

分 类 号：R442.5[医药卫生—诊断学]