男性泌尿生殖道支原体感染及药敏分析  

Analysis of Mycoplasma Infection in Male Genitourinary System and Its Drug Sensitivity

作　　者：伍拓[1] 汤育新[1] 吴萍辉[1] 谌安君[1] 

机构地区：[1]中南大学湘雅三医院泌尿外科,湖南长沙410013

出　　处：《微生物学杂志》2009年第5期104-106,共3页Journal of Microbiology

摘　　要：探讨男性尿道炎患者支原体感染率及其敏感性,为临床治疗支原体感染导致的疾病提供合理用药的参考依据。采用海泰生物的支原体分离鉴定试剂盒,取前列腺液或尿道分泌物,对1 116份疑为泌尿生殖系统感染的男性患者进行了支原体检测和抗生素敏感性检测。1 116份男性患者标本中共分离出274株支原体,242株Uu对美满霉素、强力霉素、环丙沙星、司帕沙星、氧氟沙星、阿齐霉素、罗红霉素、交沙霉素、克拉霉素、壮观霉素的敏感率分别为95.1%、94.6%、17%、70.3%、31.1%、76%、77.7%、92.6%、83.5%、43.8%。30株Uu+Mh对美满霉素、强力霉素、环丙沙星、司帕沙星、氧氟沙星、阿齐霉素、罗红霉素、交沙霉素、克拉霉素、壮观霉素的敏感率分别为70%、66.7%、20%、40.1%、26.8%、23.4%、23.4%、50%、23.3%、20%。泌尿生殖道支原体的耐药性监测对指导临床治疗具有重要意义,可以根据药敏结果指导临床合理使用抗菌药物。In order to provide a reasonable medicine using reference foundation for clinic treatment against Mycoplasma infection in male urethritis patients, the infection rate and drug sensitivity were investigated. Haitai Biology Mycoplasma isolation and characterization reagent kit was used to test and determine 1 116 samples from prostate and urethral secretion of susceptible male patients and test their antibiotic sensitivities. The results showed that 274 Mycoplasma strains were isolated from the samples, and sensitivity rates were as follow （ % ） ： mynicycline （95.1） , doxycycline （ 94.6 ）, ciprofloxacin （ 17 ）, sparfloxacin （70. 3 ）, ofloxacin （ 31. 1 ）, azithromycine （ 76 ）, roxithromycin （77.7）, josamycine （92.6）, clatythromycine （83.5）, and spectinomycine （43.8） for 242 isolates of Uu minocycline （70）, doxycycline （66.7）, ciprofloxacin （20）, sparfloxacin （40. 1 ）, ofloxacin （26. 8 ）, azithromycine （ 23.3 ） , and spectinomycin （20） for 30 isolates of Uu ＋ Mh. Therefore, monitoring drug sensitivity of urogenital Mycoplasma strains has important clinical significance in treatment, it could instruct the reasonable application of antibiotic medicine according to the medicine sensitivity results in clinic.

关 键 词：支原体感染 解脲脲原体 人型支原体 耐药性 

分 类 号：R375.3[医药卫生—病原生物学]