中国大陆2009年早期确诊的420例甲型H1N1流感病例流行病学特征分析  

Epidemiological characteristics of 420 influenza A （H1N1） cases confirmed in the early stage of the epidemic in China's Mainland

作　　者：李亚品[1] 钱全[1] 方立群[1] 杨红[1] 魏茂提[1] 高燕[2] 杨华[2] 张勇[3] 曹务春[1] 

机构地区：[1]军事医学科学院微生物流行病研究所病原微生物生物安全国家重点实验室,北京100071 [2]中国疾病预防控制中心病毒病预防控制所病毒基因工程国家重点实验室 [3]北京师范大学

出　　处：《中华流行病学杂志》2009年第11期1102-1105,共4页Chinese Journal of Epidemiology

基　　金：国家“十一五”科技重大专项（2008ZX10004-012,2009ZX10004-720）;国家“863”高技术研究发展计划（2007AA12Z240）

摘　　要：目的了解中国大陆2009年早期（5月11日至6月22日）确诊的甲型H1N1流感病例的流行病学特征。方法应用描述性流行病学方法对中国大陆2009年早期确诊的420例甲型H1N1流感病例的年龄、性别、来源、主要症状、潜伏期等流行病学特征进行分析。结果中国大陆早期诊断的甲型H1N1流感病例中输入性病例占总病例数的77．8％，主要由美国、加拿大、澳大利亚三个国家输入，占中国大陆总输入性病例的90％；所有患者中男性占53％，平均年龄22岁（22．2岁±14．9岁）；早期确诊的甲型H1N1病例以发热（81％）、咳嗽（40％）、咽痛（35％）等症状为主；输入性病例从入境到发病平均2．5d±1．9d（1—11d），二代甲型H1N1流感病例的平均潜伏期为4．3d±1．7d（1～8d）。结论中国早期确诊的甲型H1N1流感病例以输人性病例为主；其性别构成与输入国相类似，而年龄构成不同；早期确诊患者以上呼吸道感染症状为主；输入性病例从入境到发病平均2．5d±1．9d（1—11d），二代病例平均潜伏期为4．3d±1．7d（1～8d）。Objective To describe the epidemical characteristics of A （H1N1） influenza identified in the early stage（from May 11 to June 22, 2009） of the epidemic, in China's Mainland. Methods Epidemical characteristics of 420 confirmed A （H1N1） influenza cases reported from May 11 to June 22, 2009 were analyzed descriptively, including the distribution of age, sex, source of infection, main symptoms and incubation period. Results A total of 77.8% early cases in China's Mainland were imported from other countries. Three countries including America, Canada and Australia were attributed to 90% of the imported cases. Most of the cases were from 6 months to 73 years old, with 94% of them under 50 years. Most of the symptoms would include fever （81%）, cough （40%） and sore throat （35%）. The mean incubation period of second-generation cases was 4.3 （4.2 ± 1.5） days. Conclusion Imported cases dominated the total cases in the early stage of the epidemic had similar gender distribution of those from exporting countries. Fever, cough and sore throat were the three main symptoms manifested in influenza cases. 2.5 ± 1.9（ 1-11 ）days was found in imported cases between the day of off-board and the onset of symptoms. The incubation period was 4.3±1.7 （1-8） days among the secondary cases.

关 键 词：甲型H1N1流感 流行病学特征 

分 类 号：R511.7[医药卫生—内科学] R181.3[医药卫生—临床医学]