试论心室重构及其药物逆转  

Left ventricular remodeling mechanism and its medical reversion

作　　者：宛霞[1] 徐康康[1] 

机构地区：[1]南京医科大学附属南京儿童医院,江苏南京210008

出　　处：《安徽医药》2009年第11期1409-1410,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：重构(remodeling)由Baumbach等在1989年首次提出。高血压左室重构是心脏事件的重要独立危险因素,与心率失常,猝死,心力衰竭等密切相关。现已证明,在高血压情况下,心血管系统会发生相应的结构和功能的变化,这与高血压的预后密切相关。高血压时心脏的前后负荷增加,血流动力学改变伴随神经—内分泌异常,左心室肥厚以及心腔扩大,此过程即为左心室重构。本文就心室重构的机制及其药物逆转做一综述。Remodeling was firstly offered by Baumbach in 1989.Left ventricular remodeling in essential hypertensive disease is an important individual risky factor which has close relationship with cardiac arrhythmia,scd and heart failure.It has been proved that cardiac system will undergo a set of changes in construction and function when the patient has essential hypertensive disease.Essential hypertensive disease will increase heart burden as well as endocrine system disorder,lvh and heart enlargement.This process is called left ventricular remodeling. This article is a conclusion of left ventricular remodeling mechanism and its medicical reversion.

关 键 词：左心室重构 药物逆转 心血管系统 内分泌异常 

分 类 号：R541[医药卫生—心血管疾病]