微波辐射无溶剂体系中硅胶负载铌酸催化合成α-D-葡萄糖五乙酸酯  

Synthesis of α-D-glucose Pentaaccetate on HNb_3O_8·H_2O/SiO_2 Catalyst

作　　者：许招会[1] 周鹏[1] 廖维林[1] 熊云奎[1] 

机构地区：[1]江西师范大学江西省精细化工重点实验室,江西南昌330027

出　　处：《化学世界》2009年第11期685-687,684,共4页Chemical World

摘　　要：研究了在硅胶负载铌酸的催化条件下,以葡萄糖和乙酸酐为原料,通过微波辐射,无溶剂合成了-αD-葡萄糖五乙酸酯。考察了微波辐射功率、微波辐射时间、糖酐摩尔比及催化剂用量等因素对反应的影响。确定了其最佳反应条件为:取0.1 mol葡萄糖,n(葡萄糖)∶n(乙酸酐)=1.0∶6.0,催化剂用量为0.4 g/0.1 mol葡萄糖,微波功率280 W,反应时间10 min在此条件下酯收率可达94.1%。α-D-glucose pentaacetate was synthesized in solvent-free condition from glucose and acetic anhydride with HNb3O8 · H2O/SiO2 as catalyst under microwave irradiation. The effects of microwave- irradiation power, microwave-irradiation time, molar ratio of glucose to acetic anhydride, and catalyst dosage on the yield were investigated. The optimum conditions were as follows. 0. 1 mol glucose, n （glucose） ： n（acetic anhydride）=1. 0 ： 6.0 （mol/mol）, 0.4 g HNb308 · H2O/SiO2/0. 1 mot glucose, the microwave-irradiation power of 280 W, and the microwave-irradiation time of 10 min. The ester yield was up to 94. 1 %.

关 键 词：α-D-葡萄糖五乙酸酯 酯化 硅胶负载铌酸 

分 类 号：TQ457.2[化学工程—农药化工]