2型糖尿病患者合并勃起功能障碍对心血管病风险预测的研究  

The Predictive Role of Diabetes Mellitus With Erectile Dysfunction on Cardiovascular Risk

作　　者：韦秀英[1] 胡世红[2] 李占全[3] 龙入虹[1] 梁晓[1] 肖丽红[1] 钟萍[1] 郑杨杨[1] 

机构地区：[1]广西医科大学第五附属医院内分泌科,广西省柳州市545001 [2]广西医科大学第五附属医院心内科,广西省柳州市545001 [3]广西医科大学第五附属医院男性科,广西省柳州市545001

出　　处：《中国循环杂志》2009年第5期371-374,共4页Chinese Circulation Journal

基　　金：广西卫生厅科研项目(z2006095)

摘　　要：目的:了解2型糖尿病患者合并勃起功能障碍(ED)时是否有心血管病的风险。方法:对2型糖尿病合并勃起功能障碍组(ED组)71例,2型糖尿病无勃起功能障碍组(非ED组)45例,测量其颈内动脉内膜中层厚度(IMT),同时测量身高、体重、血压、血脂、血糖、C肽等。比较两组间平均颈内动脉IMT及血糖、血脂等代谢指标。结果:平均颈内动脉IMT比较:ED组明显厚于非ED组(P<0.05);血清总胆固醇、低密度脂蛋白胆固醇:ED组明显高于非ED组(P<0.05);在2型糖尿病患者中,ED评分与颈内动脉IMT呈负相关(r=-0.321,P=0.000)。结论:2型糖尿病患者合并ED时其患动脉粥样硬化的危险性要高于不合并ED者,2型糖尿病合并ED可能是心血管病的一个早期预警信号。Objective：To investigate the role of type 2 diabetes mellitus （DM）with erectile dysfunction（ED） in cardiovascular risk. Methods：A total of 71 DM patients with ED（ ED group）and 45 DM patients without ED （Non-ED group）were recruited in this study. Carotid artery intima-media thickness （IMT） of all enrolled subjects was measured. Meanwhile, their height, weight, blood pressure, blood lipids, blood glucose and C peptide were evaluated. The differences of above index between the two groups were statistically compared. Results：Carotid internal artery IMT in ED group was significantly thicker than that in Non-ED group（ P 〈 0.05 ）. Blood total cholesterol and low-density lipoprotein cholesterol in ED group were also obviously higher than that in Non-ED group（P 〈 0. 05 respectively）. The ED scores in patients with DM showed inverse correlation with carotid internal artery IMT（ r = -0. 321 ,P = 0. 000）. Conelusion：DM patients with ED were more likely to suffer from artheroselerosis than DM without ED whieh suggesting that DM with ED might be an early warning sign to cardiovascular risk.

关 键 词：糖尿病 勃起功能障碍 心血管病 风险预测 颈内动脉内膜中层厚度 

分 类 号：R541[医药卫生—心血管疾病]