高通量血液透析联合血液灌流治疗尿毒症顽固性高血压的观察  

Effects of Combined Therapy with High-flux Hemodialysis and Hemo-perfusionin Uremic Patients with Refractory Hypertension

作　　者：陈曦[1] 

机构地区：[1]哈尔滨医科大学第四临床医学院血透科,黑龙江哈尔滨150001

出　　处：《黑龙江医学》2009年第8期598-600,共3页Heilongjiang Medical Journal

摘　　要：目的观察高通量血液透析(HFHD)联合血液灌流(HP)治疗尿毒症患者顽固性高血压(RH)的疗效。方法将44例尿毒症伴RH患者随机分为HFHD组和HFHD+HP组。HFHD组行每周2次HD加每周1次HFHD;HFHD+HP组在HFHD组基础上,每2周联合1次HP,治疗12周,比较两组患者治疗前后平均动脉压和降压药种类情况。结果治疗后,两组患者平均动脉压及降压药种类均下降,与治疗前相比有差异(P<0.05),尤以HFHD+HP组明显(P<0.01),治疗后两组结果相比亦有显著差异(P<0.05)。结论高通量血液透析对尿毒症顽固性高血压治疗有效,联合血液灌流疗效更佳。Objective To observe the effects of combined therapy with high- flux hemodialysis（HFHD） and hemoperfusion（HP） in uremic patients with refractory hypertension（RH）. Methods Forty - four patients with refractory hypertensio9 caused by uremia were divided randomly into 2 groups： HFI-ID group, in which the patients were given HD twice a week and HFHD once a week; HFHD and HP group, in which the patients were given HP once every two weeks, based on the therapy of the HFHD group. We compared the mean artenial pressure and the species of hypotensor before and after treatment after 12 weeks. Results After treatment the mean artenial pressure and the species of hypotensor both decreased significantly in the two groups（ P 〈 0.05）, but those changes in the HFHD and HP group were more obvious （ P 〈 0.01）,the results of the HFHD and HP group were better than the HFHD group（ P 〈 0.05）. Conclusion HFHD were effective in the treatment of refractory hypertension caused by uremia and the combined thempy with HFHD and lip might be a comparatively more effective way.

关 键 词：高通量血液透析 血液灌流 尿毒症 顽固性高血压 

分 类 号：R459.5[医药卫生—治疗学]