跑台运动对去卵巢大鼠体重、腹腔内脂肪重量和血脂的影响  

Effects of Treadmill Exercise on the Body Weight,Intra-abdominal Fat Mass and Serum Lipids in Ovariectomized Rats

作　　者：王怡靖[1] 卜淑敏[1] 杨俊卿[1] 

机构地区：[1]首都体育学院,北京100088

出　　处：《首都体育学院学报》2009年第6期710-712,共3页Journal of Capital University of Physical Education and Sports

基　　金：国家自然科学基金(30771046);北京市教委科技发展规划项目(KM200710029001);北京市教委人才强教中青年骨干教师项目资助

摘　　要：为了观察中等强度跑台运动对去卵巢大鼠体重、腹腔内脂肪重量和血脂水平的影响,将雌性3月龄SD大鼠,按体重随机分为假手术、去卵巢和去卵巢运动3个组。去卵巢运动组大鼠每天进行60min、速度18m/min、无坡度的电动跑台训练,每周5次,共12周。实验结束后,称体重和腹腔内脂肪重量;氧化酶法测定血清总胆固醇(TC)和甘油三酯(TG)水平;直接测定法检测高密度脂蛋白(HDL-C)水平。结果表明:去卵巢组体重、体重增加量、腹腔内脂肪绝对重量和相对重量、血清TC水平均显著高于假手术组,血清TG水平、HDL-C/TC比值显著低于假手术组,而HDL-C水平无显著变化;12周跑台运动后,去卵巢运动组腹腔内脂肪绝对重量和相对重量显著低于假手术组,HDL-C/TC的比值显著高于去卵巢组,而体重和其他血脂指标无显著变化。以上结果提示,中等强度跑台运动能抑制去卵巢大鼠腹腔内脂肪重量的增加,部分改善血脂水平。To observe the effects of treadmill exercise of medium intensity on the body weight,intra-abdominal fat mass and serum lipids levels in ovariectomized rats,three-month-old female Sprague-Dawley rats were divided randomly into three groups：sham operation,ovariectomized （OVX） and treadmill exercise prevention group according to the body weight.The exercise group ran on the treadmill at a speed of 18m.min-1 without slope,60min for 12 weeks.At the end of the experiment,all the animals were weighted and killed, with their blood collected for serum and intra-abdominal fats removed. Total cholesterol （TC）, triglycerides （TG）, high-density lipoprotein-cholesterol （HDL-C） levels were tested. The results indicated that ovariectomized treatment not only significandy increased the body weight,accumulation of intra-abdominal fat,and serum TC levels, but also decreased the serum TG and the ratio of HDL-C to TC. In addition, treadmill exercise treatment significantly inhibited the increase of intra-abdominal fat and increased the ratio of HDL-C to TC,but had no effect on body weight and other serum lipid levels. The results suggested that treadmill exercise of medium intensity can inhibit the increase of the intra-abdominal fat and benefit partly the disorder of serum lipids induced by ovariectomy.

关 键 词：去卵巢大鼠 运动 肥胖 雌激素 血脂 

分 类 号：G804.2[文化科学—运动人体科学]