60例类风湿关节炎患者手部影像学资料分析  

Radiological Analysis of the Hand in 60 Patients with Rheumatoid Arthritis

作　　者：赵臻怡[1] 杨南萍[1] 刘潇潇[1] 张杰[1] 李敏[1] 叶扬[1] 石连杰[1] 钟雪[1] 

机构地区：[1]四川大学华西医院风湿免疫科,四川成都610041

出　　处：《华西医学》2009年第8期2076-2077,共2页West China Medical Journal

摘　　要：目的:探讨类风湿关节炎(RA)患者手部X线的表现与临床指标关系。方法:对60例临床资料完整的RA病例行双手正侧位X线检查,分为符合类风湿关节炎X线I期表现的32例(第1组),符合类风湿关节炎Ⅱ期及以上表现的患者28例(第2组),分别统计类风湿关节炎患者的临床指标类风湿因子(RF)、红细胞沉降率(ESR)、C反应蛋白(CRP)和关节肿胀个数进行两组比较,以及对影像学Sharp评分和临床各指标相关性进行评价分析。结果:两组RA患者的RF、ESR、CRP和关节肿胀数第2组明显高于第1组,两组差异均具有显著性(P<0.05),Sharp评分与ESR、CRP、RF、关节肿胀数均有相关性,它们的r值、P值分别为r=0.414,P=0.001;r=0.481,P=0.000;r=0.333,P=0.009;r=0.261,P=0.044。结论:类风湿关节炎Ⅱ期及以上表现的患者RF、ESR、CRP和关节肿胀数明显高于类风湿关节炎X线Ⅰ期表现的患者,Sharp评分和RF、ESR、CRP和关节肿胀数有一定相关性,说明RF、ESR、CRP和关节肿胀数对类风湿关节炎的预后有预测作用。Objective：To study the relationship between clinical manifestation and hand X-ray in rheumatoid arthritis（RA）.Methods：Two groups were divided,one had 32 RA patients with grade Ⅰ X-ray,and the other had 28 RA patients with grade Ⅱ and above X-ray.Levels of rheumatoid factor（RF）,erythrocyte sedimentation rate（ESR）,C reactive protein（CRP）,the number of swollen joints were detected and to evaluate the relations between the modified Sharp s radiological progression scores and RF,ESR,CRP,the number of swollen joints. Results： There were difference of RF, ESR, CRP, the number of swollen joints between the two groups （P〈0. 05）. There was closely relationship between the modified Sharp＇s radiological progression scores and RF, ESR, CRP, the number of swollen joints. The related quotieties were 0. 414, 0. 481, 0. 333, 01 261. Conclusion： RF, ESR, CRP, the number of swollen joints would predict radiographic joint damage in patients with early RA.

关 键 词：类风湿关节炎 X线检查 类风湿因子 C反应蛋白 

分 类 号：R593.22[医药卫生—内科学] R739.41[医药卫生—临床医学]