正常和嵌合肿瘤乳腺温度分布特征的有限元分析  

Finite Element Analysis for Temperature Characteristics of Normal and Embedded Tumor Female Breast

作　　者：杨洪钦[1] 许啊清[1] 王瑜华[1] 谢树森[1] 叶真[2] 苏毅明[2] 

机构地区：[1]福建师范大学激光与光电子技术研究所,福建省光子技术重点实验室,医学光电科学与技术教育部重点实验室,福建福州350007 [2]福建医科大学附属第一医院,福建福州350005

出　　处：《光学学报》2009年第11期3173-3178,共6页Acta Optica Sinica

基　　金：国家自然科学基金(60578056);福建省自然科学基金(2006J0091);福建省青年科技人才创新基金(2007F3026);福建师范大学优秀青年骨干教师培养基金(2008100218)资助课题

摘　　要：基于乳腺解剖学结构和生理学特征,建立了适合应用于正常和嵌合肿瘤乳腺三维热传递的分析模型。该模型综合考虑了乳腺代谢产热、血液灌注和动静脉血管与乳腺组织之间的热交换等因素对温度场的影响。数值研究了正常和嵌合肿瘤乳腺的温度分布特征,着重分析代谢产热、血液灌注率、乳腺肿瘤的大小、位置与数目以及空气对流系数、环境温度等因素对乳腺温度分布的影响。结果表明:血液灌注率、代谢产热、乳腺肿瘤的大小、位置与数目对乳腺温度分布特征的影响明显;环境条件对嵌含肿瘤乳腺的体表温度分布影响较大。研究结果将有助于指导乳腺红外热图像的实验并为其定性分析提供重要的参考。Based on the breast anatomical structure and physiological characteristics, a three-dimensional thermal model for normal and embedded tumor breast which considered the metabolic heat generation, blood perfusion and heat exchange between vascular and breast was established. Finite element method was used to solve this model for numerically simulating the temperature distribution of breast, and then the effects of various factors, such as blood perfusion, metabolic heat generation, the size, location and numbers of breast tumor, air convection coefficient and environmental temperature on the temperature distribution of breast were discussed. The results show that the temperature profiles of breast could be significantly affected by the metabolic heat generation, blood perfusion, tumor size, tumor position and numbers, while the surface thermal expression of embedded tumor breast could be influenced by the air flow and environmental temperature. This study results may guide the experiment of breast thermograms and provide important reference for its qualitative analysis.

关 键 词：医用光学 三维温度分布特征 有限元法 乳腺 肿瘤 

分 类 号：TK124[动力工程及工程热物理—工程热物理] R445.7[动力工程及工程热物理—热能工程]