可乐定和罗哌卡因用于硬膜外自控镇痛治疗顽固性心绞痛的效果观察  

The Clinical Effect of Clonidine Associate with Ropivacaine Patientcontrolled Thoracic Epidural Analgesia(PCTEA) in Patients with Pertinacity Angina Pectoris

作　　者：周彤[1] 

机构地区：[1]天津市河西区柳林医院麻醉科,天津300222

出　　处：《中国医药导刊》2009年第11期1884-1886,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:观察可乐定和罗哌卡因用于胸部硬膜外自控镇痛治疗顽固性心绞痛的效果。方法:选择因顽固性心绞痛入院治疗的内科病人90例。选择T3-4椎间隙施行硬膜外,应用0.15%罗哌卡因5ml注入硬膜外腔作为负荷剂量,自控镇痛注药泵内药液为0.075%可乐定+0.15%的罗哌卡因200ml,镇痛采用LCP模式进行镇痛。分别记录镇痛开始后4h,24h,2天,4天,7天,8天的VAS视觉模拟疼痛评分,舒适度,PCA加药次数,同步12导联标准心电图监测结果及治疗的不良反应。结果:患者镇痛质量、舒适度比较和体征均有明显改善。TEA前后,NST及∑ST均有显著减少。结论:可乐定和罗哌卡因用于胸部硬膜外自控镇痛治疗顽固性心绞痛,效果可靠、安全。Objective：To observe the clinical effect of clonidine associate with ropivacaine patient-controlled thoracic epidural analgesia（PCTEA） in patients with pertinacity angina pectoris.Methods：90 medical patients with angina pectoris in liulin hospital .All patients was used 0.075% clonidine＋0.15% ropivacaine patient-controlled thoracic epidural analgesia was provided by PCA pump with LCP model. the following were recorded： 4h to 8d pain intensity evaluated using VAS, Braggmann comfort scale and side effects reaction.Results：①All patients were showed significant difference in the analgesia effects, comfortable, improve symptom than before the therapy.②The sites of ST depression and total ST depression of 12 sites of ECG decreased significantly compared with previous accepting PCTEA therapy.Conclusions： Ctonidine associate with ropivacaine was used of Patient-controlled thoracic epidural analgesia is effective and safe for patients with pertinacity angina pectoris.

关 键 词：可乐定 罗哌卡因 胸部硬膜外阻滞 心绞痛 效果 

分 类 号：R541.4[医药卫生—心血管疾病]