药物对磷酸钙骨水泥性能的影响综述  

Review of Effect of Drug on Property of Calcium Phosphate Cement

作　　者：李茂红[1,2] 屈树新[2] 姚宁[2,3] 郭悦华[2] 王岳峰[1] 翁杰[2] 

机构地区：[1]西南交通大学峨眉校区基础课部,峨眉614202 [2]西南交通大学材料科学与工程学院材料先进技术教育部重点实验室,成都610031 [3]西南交通大学生命科学与工程学院,成都610031

出　　处：《材料导报》2009年第21期55-58,共4页Materials Reports

基　　金：国家自然科学基金(30470484)资助项目;教育部新世纪人才基金(NCET-05-0797)资助项目;西南交通大学峨眉校区基金(10801X10096010)资助项目

摘　　要：药物载入磷酸钙骨水泥(CPC)可能会导致CPC凝结时间、力学性能等发生变化。难溶于水的药物与CPC接触形成的固-固界面相互间作用较弱,在载入量不太高时对CPC凝结时间、力学性能影响较小。而易溶于水的药物则可能导致CPC界面性质、酸碱性、转化过程等发生变化,从而对CPC凝结时间、力学性能等产生影响。CPC凝结时间和力学性能分别是衡量手术可操作性的重要指标和决定CPC应用范围的重要参数,就药物载入后对CPC凝结时间、力学性能的影响进行了综述。The drug loaded into calcium phosphate cement（CPC） which might have an effect on the setting time and mechanical property of CPC. The insoluble drug has little effect on the setting time and mechanical property of CPC when the quantity of drug loaded is not too much, which attributes to the weak interaction of the solid-solid interface. The soluble drug has an effect on the setting time and mechanical property of CPC, which might be concerned with the change of the interface property, the pH value, and the hydration course of CPC. The setting time and mechanical property of CPC are the important parameters which decide the maneuverability of the operation and the application of CPC. The effect of the drug on the setting time and mechanical property of CPC are reviewed.

关 键 词：磷酸钙骨水泥 凝结时间 力学性能 药物 影响 

分 类 号：TQ172.7[化学工程—水泥工业] TQ172.12[化学工程—硅酸盐工业]