聚磷酸钙及其复合材料的研究进展  

Progress of the Research on CPP Composites

作　　者：冯超阳[1] 崔园园[1] 张琳琳[1] 张志斌[1] 

机构地区：[1]西南交通大学生命科学与工程学院,成都610031

出　　处：《材料导报》2009年第23期43-46,共4页Materials Reports

基　　金：国家自然科学基金资助项目(50573061);四川省应用基础研究项目(07JY029-065);西南交通大学科学研究基金资助项目(2006B52)

摘　　要：聚磷酸钙(Calcium polyphosphate,CPP)具有优异的生物相容性、生物活性、良好的骨传导性和可生物降解性,其钙磷比为0.5,是具有聚合重复单元的陶瓷基新型无机聚合生物材料,与骨组织有相似的化学成分。另外CPP降解后所释放的钙离子和磷酸根离子参与体内钙磷代谢,被重新沉积到骨组织中,可以加速骨组织矿化促进形成新骨,所以CPP作为一种新型的骨组织替代生物材料已成为研究的热点。详细介绍了CPP及其复合材料的制备、力学性能及生物学性能,对CPP的进一步研究和开发将赋予其更广阔的应用前景。Calcium polypbosphate（CPP） has excellent biocompatibility, bioactivity, good bone conduction and biodegradability,and its calcium and phosphorus ratio is 0.5, so CPP is a new ceramic inorganic polymer matrix biological material with polymerizing repeated units, which has similar chemical composition with bone tissue. In addition, the calcium and phosphate ions released from the degradation of CPP will participate calcium and phosphorus metabolism in the body, be redeposited into bone tissue, accelerate the mineralization of bone tissue and promote the formation of new bon~ Thereby CPP as a new type of biological material substituted for bone tissue has become a research hotspot. This paper clearly introduced the preparation, mechanical and biological properties of CPP and its composite materials. With further research and development, CPP will be given a wider application.

关 键 词：聚磷酸钙(CPP) 骨修复材料 骨组织工程 纤维 

分 类 号：TB33[一般工业技术—材料科学与工程] S816[农业科学—饲料科学]