京大戟石油醚提取部分化学成分的研究  

Study on Chemical constituents from the part of petroleum ether extract of Euphorbia pekinensis

作　　者：姜文红[1] 刘静[2] 麻风华[1] 哈莉莉[2] 仲昭庆[1] 张清波[1,2] 戴忠[3] 马双成[3] 

机构地区：[1]黑龙江省药品检验所,黑龙江哈尔滨150001 [2]黑龙江中医药大学,黑龙江哈尔滨150040 [3]中国药品生物制品检定所,北京100050

出　　处：《中医药信息》2009年第6期15-16,共2页Information on Traditional Chinese Medicine

基　　金："十一五"国家科技支撑计划重点项目(2006BAI14B01)

摘　　要：目的:对京大戟(Euphorbia pekinensis Rupr.)进行化学成分研究。方法:采用溶剂提取、硅胶、ODS柱色谱及制备HPLC等进行分离纯化,根据化合物的理化性质和波谱数据鉴定结构。结果:从京大戟的石油醚提取部分分离得到3个化合物,分别鉴定为24-亚甲基-环阿尔廷醇(Ⅰ),大戟醇(Ⅱ),甘遂甾醇(Ⅲ)。结论:化合物Ⅰ系首次从该植物中分离得到。Objective:To study the chemical constituents from Euphorbia pekinensis. Methods:The components were isolated by means of sol- vent extraction, silica gel and ODS column chromatography and prepar- ative HPLC. The structures were elucidated by their physiochemical characteristics and spectral data. Results: Three compounds were iso- lated and elucidated as 24-methene-cycloartenol (Ⅰ) , euphol (Ⅱ) , tirucallol (Ⅲ). Conclusion: Compound Ⅰ were obtained from Euphorbia pekinensis for the first time.

关 键 词：京大戟 大戟科 三萜化合物 

分 类 号：R284.1[医药卫生—中药学]