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作 者:Eleonora Cominelli Chiara Tonelli
出 处:《Cell Research》2009年第11期1231-1232,共2页细胞研究(英文版)
摘 要:MYB proteins are transcription factors present in all eukaryotes, sharing a common DNA-binding domain that consists of one to three imperfect helix-helix-turn-helix repeats of about 50 amino acids, called R1, R2, and R3 respectively . In animals and yeast these proteins represent a small gene family . Animal RIR2R3-MYB proteins have been described for their role in cell cycle regulation mainly at the G1/S, but also at the G2/M transition, as firstly demonstrated in Drosophila .
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