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机构地区:[1]陕西中医学院附属医院磁共振室,陕西咸阳712000
出 处:《第四军医大学学报》2009年第21期2435-2437,共3页Journal of the Fourth Military Medical University
摘 要:目的:探讨Balo病同心圆硬化(BCS)的磁共振表现特征及其病理基础.方法:回顾性分析4例Balo病同心圆硬化患者的MRI表现,均经激素治疗临床症状好转后行MRI复查.结果:4例患者中,1例单发,3例多发,最多者病灶5个.病变主要累及大脑半球皮层下和深部白质区,共发现11个病灶,其中顶叶半卵圆中心和颞叶的发病比例高.典型同心圆样病灶8个,直径1~2.3cm,同心圆层数为3~5个.在T1WI加权像呈等、低信号相间;T2WI,FLAIR像上呈等、高信号交替环,病灶周围有轻度水肿表现,上述表现与镜下脱髓鞘区与髓鞘保留区相间相对应.其余3个不典型的病灶呈斑片状或煎蛋样改变;增强后1例病灶呈点状或边缘线状强化.结论:Balo病同心圆性硬化的MRI及其增强扫描具有特征性表现,可作为本病诊断的主要方法,并可用于疗效的观察.AIM:To evaluate the correlation between the features on MR and pathologic finding of the Balo s concentric sclerosis(BCS). METHODS:MRI manifestations of four cases with Balo s concentric sclerosis were reviewed,all treated with steroid and after the clinical symptoms alleviated,performed the MRI examination. RESULTS:Of the 4 cases,11 lesions showed on MRI.Solitude lesion and multitude lesions occourred in 1 case and 3 cases,respectively.They mainly distributed on the subcortex of cerebral hemispheres and deep part white matter, especiallylocated at centrum ovale and temporal lobe. Among them,8 lesions appeared as characteristic concentric structure. T1 weighted revealed 3 - 5 concentric rings with diameters ranging from 1 to 2. 3 cm alternating between hypo- and iso-intensity signal zones. On T2-weighted, fluid-attenuated inversion-recovery pulse sequence (FLAIR) ,the above-mentioned rings focus appeared as iso- and hyper-intensity signal with slightly surrounding swelling and poorly defined margin. The diameters were slightly longer than on T1 WI, this finding being consistent with pathological results. Three atypia lesions showed as patching or fried egg. There was 1 to 3 semi-circumi structure within the lesion. On Gd-DTPA enhanced MR scans, lightly liner-like enhancement occurred in one patient. CONCLUSION: Balo's concentric sclerosis has specific MRI and enhancement features, MRI can be used as a main method for the disease and to evaluate the treat effect.
分 类 号:R445[医药卫生—影像医学与核医学]
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