踝臂指数评价2型糖尿病合并下肢外周动脉病患者疗效中的临床价值  

Clinical Application of Ankle-Brachial Index in the Treatment of Peripheral Arterial Disease in the Patients with Type 2 Diabetes Mellitus

作　　者：赵季红[1] 孙婧[1] 杨宁[1] 石蕊[1] 姜铁民[1] 李玉明[1] 

机构地区：[1]中国人民解放军武警医学院附属医院心内科,天津市300162

出　　处：《中国动脉硬化杂志》2009年第9期771-773,共3页Chinese Journal of Arteriosclerosis

摘　　要：目的观察踝臂指数在2型糖尿病合并下肢外周动脉病患者治疗前后的变化,以探讨踝臂指数作为其疗效评价指标的可行性。方法2型糖尿病合并下肢外周动脉病患者112例,分为单纯药物治疗组(62例)和介入治疗+药物治疗组(50例)。详细记录每一患者的临床资料,包括年龄、性别、身高、体重、心率、血压、空腹血糖、餐后2 h血糖、糖化血红蛋白和血脂等结果。并分别于治疗前和治疗后1个月、3个月、6个月测踝臂指数。结果2型糖尿病合并下肢外周动脉病患者治疗前踝臂指数小于0.90。介入治疗+药物治疗组治疗后1个月、3个月和6个月的踝臂指数与治疗前相比均有统计学意义(P<0.05),与单纯药物治疗组同期相比亦均有统计学意义(P<0.05)。单纯药物治疗组治疗后1个月、3个月和6个月的踝臂指数与治疗前相比无明显变化(P>0.05)。结论踝臂指数在2型糖尿病合并下肢外周动脉病患者的治疗中起重要指导作用。介入治疗能够及早改善2型糖尿病合并下肢外周动脉病患者的血运,比单纯药物治疗疗效显著。Aim To investigate the clinical application of ankle-brachial index （ABI ） in the treatment of peripheral arterial disease in the patients with type 2 diabetes mellitus. Methods 112 type 2 diabetic patients with peripheral arterial disease were randomly divided into drug treatment group （ n = 62 ） and interventional therapy and drug treatment group （ n = 50 ）. All patients were checked for ABI by automatic analysis system of angiosclerosis. Results ABI was less than 0.90 in type 2 diabetic patients with peripheral arterial disease before therapy. ABI was increased in type 2 diabetic patients with peripheral arterial disease after interventional therapy and drug treatment （ P 〈 0.05 ）. ABI was not increased in type 2 diabetic patients with peripheral arterial disease after drug treatment （ P 〉 0.05 ）. Conclusion ABI is significant in type 2 diabetic patients with peripheral arterial disease who had taken the interventional therapy.

关 键 词：踝臂指数 2型糖尿病 下肢外周动脉病 介入治疗 

分 类 号：R5[医药卫生—内科学]