4、5、6、7单氟代吲哚-2-酮的合成工艺综述  

Review on synthesis of 4-,5-,6-or 7-mono-fluoro substituted indol-2-one

作　　者：鲍书馨[1] 方正[1] 韦萍[1] 

机构地区：[1]南京工业大学制药与生命科学学院,江苏南京210009

出　　处：《化学试剂》2009年第11期900-902,954,共4页Chemical Reagents

摘　　要：氟代吲哚-2-酮多用于现代医药化工业中,可以作为多种药物重要中间体。经过文献查阅,综述了吲哚酮4、5、6、7位置氟取代化合物的合成方法,一共给出12条路线。4-, 5-, 6-or 7-mono-fluoro substituted indol-2-one is used in modern medical and chemical engineering as intermediates for manufacture of many kinds of medicine. The main methods for synthesis of indolone which were substituted by fluorine at the 4-, 5-, 6- or 7-position were reviewed in this paper by referring to literature information, and 12 synthesis routes were given.

关 键 词：氟代吲哚酮 合成 工艺 

分 类 号：O626[理学—有机化学]