同种异体鼻中隔四方软骨修补鼻中隔穿孔:9例报告  

Homogeneity variant quadratic cartilage of nasal septum for repairing of nasal septal perforation in 9 cases

作　　者：刘火旺[1] 陈志喜[2] 谭东辉[2] 孙虹[1] 陈玉[1] 陈学东[1] 贺广湘[1] 

机构地区：[1]中南大学湘雅三医院耳鼻咽喉-头颈外科,湖南省长沙市410013 [2]湘南学院附属医院耳鼻咽喉-头颈外科,湖南省郴州市423000

出　　处：《中国组织工程研究与临床康复》2009年第44期8761-8763,共3页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：湖南省自然科学基金资助项目(0JJ50030)~~

摘　　要：目的：探讨应用同种异体鼻中隔四方软骨修补鼻中隔穿孔的效果。方法：选择2004-01/2008-10在中南大学湘雅三医院耳鼻咽喉-头颈外科就诊的鼻中隔穿孔患者9例,用鼻中隔黏膜下矫正术的方法分离鼻中隔穿孔周围的黏软骨膜,取同种异体鼻中隔四方软骨固定于鼻中隔黏软骨膜下,完全覆盖鼻中隔穿孔。结果：9例患者术后48h内鼻腔无活动性出血,抽出湿润烧伤膏纱条后未见移植四方软骨移位,穿孔部位封闭。术后随访观察6-18个月,异体鼻中隔两侧面已被移行上皮完全覆盖,表面光滑。植入的同种异体鼻中隔四方软骨未见排异现象,无再穿孔。结论：同种异体鼻中隔四方软骨修补鼻中隔中、小穿孔简单、有效,无不良反应,作为一种方法可供临床参考。OBJECTIVE：To study a new treatment to repair perforation of nasal septum using the homogeneity variant quadratic cartilage of nasal septum.METHOD：Nine cases of nasal septal perforation using the homogeneity variant quadratic cartilage of nasal septum were repaired in Department of Otorhinolaryngology-Head Neck Surgery,Third Xiangya Hospital,Central South University from January 2004 to October 2008.We detach the mucosa which surround the perforation area of the nasal septum then fix the homogeneity variant quadratic cartilage of nasal septum under the mucosa of nasal septum to cover the perforation of nasal septal totally.RESULTS：No active bleeding occurred at 48 hours after operation in all cases.There was no graft shifting after expulsed the gauze.The 6-18 month follow-up showed that perforation in 9 cases was all successful with primary healing without rejection or recurrence of perforation of nasal septum.CONCLUSION：Homogeneity variant quadratic cartilage of nasal septum for repairing of nasal septal perforation is a good method without side-effects,and it can be an approach for reference in clinical purpose.

关 键 词：同种异体鼻中隔四方软骨 鼻中隔穿孔 鼻中隔穿孔修补 

分 类 号：R318[医药卫生—生物医学工程]