纯音听阈正常的耳闷患者诱发性耳声发射分析  

Analysis of evoked otoacoustic emission in normal pure tone hearing thresholds patients with aural fullness

作　　者：武斐[1] 刘吉祥[2] 张志坚[2] 毕巍[2] 申娜[1] 

机构地区：[1]天津医科大学研究生院,天津300070 [2]天津市人民医院耳鼻咽喉-头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2009年第22期1023-1026,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:对纯音听阈正常的耳闷患者进行诱发性耳声发射分析,以早期发现这些患者的耳蜗损害。方法:采用丹麦Madsen公司Capella耳声发射仪对纯音听阈正常的耳闷患者43例(72耳,耳闷组)及正常人30例(60耳,对照组)分别进行TEOAE及DPOAE检测,记录和分析各频率DPOAE的检出率、幅值,TEOAE的通过率、反应波信噪比、波形重复性及各频带反应波信噪比和重复性。结果:①DPOAE检出率仅在0.50、0.75kHz两频点上耳闷组明显低于对照组(P<0.05),其余各频率点差异均无统计学意义(P>0.05);②TEOAE通过率对照组为100%,耳闷组为90.28%,2组比较差异有统计学意义(χ2=6.16,P<0.05);③与对照组相比,纯音听阈正常的耳闷患者各频率DPOAE的幅值、TEOAE的反应波信噪比、波形重复性及各频带反应波信噪比和重复性均降低,差异有统计学意义(P<0.05或P<0.01)。结论:部分纯音听阈正常的耳闷患者已存在耳蜗外毛细胞的损害,利用诱发性耳声发射的方法可在其听力损失出现之前早期发现此类病变。Objective：To analyze normal pure tone hearing thresholds patients with aural fullness using evoked otoacoustic emission in order to detect the early cochlear impairment. Method： Forty three normal pure tone hearing thresholds patients（72 ears,aural fullness group）with aural fullness were served as subjects and 30 normal volunteers（60 ears,control group）as controls. Transiently evoked otoacoustic emission （TEOAE） and distortion prod- uct evoked otoacoustic emission （DPOAE） were tested with Cap.ella otoacoustic emission machine. The DPOAE detection rate and amplitudes at all frequencies, the passing rate and wave signal noise ratio （SNR）, wave reproducibility, band SNR and band reproducibility of TEOAE were recorded and analyzed. Result： ①Only on the frequency points of 0.50 kHz and 0.75 kHz,the detection rate of DPOAE in aural fullness group was lower than that in con trol group（P〈0.05）. There was no significant difference in the rate among other frequency points（P〉0.05）. ② The passing rate of TEOAE was 100% in control group and 90.28% in aural fullness group. There were statistical differences between two groups（X^2 = 6.16, P〈0. 05）. （3）Compared with the control group, the DPOAE amplitudes at all frequencies , the wave signal noise ratio（SNR）, wave reproducibility , band SNR and band reproducibility of TEOAE in patients with aural fullness were significantly decreased. There were statistical differences（P〈0. 05 or P〈0.01）. Conclusion：Some patients of normal hearing thresholds with aural fullness have had early harm of outer hair cell in cochlear. TEOAE and DPOAE may be used to detect these lesions early before the hearing im pairment occurred.

关 键 词：耳闷胀感 耳声发射 测听法 纯音 耳蜗 

分 类 号：R764[医药卫生—耳鼻咽喉科]