2型糖尿病住院患者非酒精性脂肪性肝病与颈动脉粥样硬化的关系  

The relationship between non-alcoholic fatty liver disease and carotid atherosclerosis in hospitalized type 2 diabetics

作　　者：王靓[1] 张静[2] 钱掩映[1] 

机构地区：[1]温州医学院附属第二医院内分泌科,浙江温州325027 [2]温州医学院附属第二医院血透中心,浙江温州325027

出　　处：《温州医学院学报》2009年第5期442-444,共3页Journal of Wenzhou Medical College

摘　　要：目的:探讨2型糖尿病住院患者非酒精性脂肪性肝病(NAFLD)与颈动脉粥样硬化的关系。方法:入选141例2型糖尿病住院患者,根据B超检查结果分为NAFLD组和无NAFLD组,均接受双颈动脉彩色多普勒超声检查,测定其内中膜厚度(IMT),观察有无斑块形成及管腔狭窄。结果:2型糖尿病合并NAFLD组颈动脉IMT增厚32例(占32.32%),斑块形成51例(占51.51%),管腔狭窄11例(占11.11%);2型糖尿病无NAFLD组颈动脉IMT增厚12例(占28.57%),斑块形成8例(占19.04%),管腔狭窄0例,两组比较,差异有显著性(均P<0.01)。结论:2型糖尿病住院患者NAFLD与颈动脉粥样硬化关系密切,对已知2型糖尿病合并NAFLD患者尽早行多部位血管超声检查有重要意义。Objective： To explore the relationship between non-alcoholic fatty liver disease （NAFLD） and carotid atherosclerosis in hospitalized type 2 diabetics. Methods： One hundred and forty-one hospitalized Type 2 diabetics were divided into NAFLD group and non-NAFLD group according to the liver B ultrasonography results, Their intima-media thickness（IMT） was detect and athero- sclerotic plaque and vessel stenosis were observed with carotid artery B-ultrasound examination. Results： In type 2 diabetics with NAFLD group,32 cases（32.32%）showed carotid IMT, 51 cases （51.51%）formation of atherosclerotic plaque,and 11 cases（11.11%）vessel stenosis;12 cases （28.57%）showed carotid IMT,8 cases（19.04%）formation of atheroscle-rotic plaque,and no vessel stenosis in the non-NAFLD group. Thus,there was a significant difference between two groups （P 〈0.01）. Conclusion： There is a close relationship between NAFLD and atherosclerosis in hospital-ized Type 2 diabetics. To do artery B-ultrasound examination early in Type 2 diabetics with NAFLD is of great significance.

关 键 词：糖尿病 2型 非酒精性脂肪性肝病 动脉粥样硬化 

分 类 号：R587.1[医药卫生—内分泌]