^(99m)Tc-TF显像在老年人甲状腺“冷结节”性质判定中的价值  

Diagnosis value of ^(99m)Tc-tetrofosmin imaging in identifying thyroid "cold nodule"

作　　者：张浩然[1] 赵劼[1] 高识[1] 马庆杰[1] 孙辉[1] 

机构地区：[1]吉林大学中日联谊医院核医学科,吉林长春130033

出　　处：《中国老年学杂志》2009年第21期2701-2703,共3页Chinese Journal of Gerontology

基　　金：吉林省科技厅科研基金资助课题(200705277)

摘　　要：目的对99m锝-1,2双〔双(2-乙氧乙基)膦基〕乙烷(99mTc-tetrofosmin,99mTc-TF)显像与颈部彩色多普勒超声(colordopplerultrasonog-raphy,CDU)检查对甲状腺"冷结节"性质判定的结果进行对比分析,以明确99mTc-TF显像在判定甲状腺"冷结节"性质中的价值。方法选择经99mTcO4-显像证实为甲状腺"冷结节"60岁以上的患者60例,以术后病理结果为标准,分别对99mTc-TF显像及颈部CDU检查在96处甲状腺"冷结节"、62处直径>1cm的甲状腺"冷结节"中的判定结果进行对比分析。结果病理结果示96处甲状腺"冷结节"中良性52处,恶性44处。颈部CDU准确率为79.17%,99mTc-TF显像准确率为77.08%,两种手段间准确率比较无显著差异(P>0.05)。病理结果示直径>1cm的62处甲状腺"冷结节"中良性34处、恶性28处。颈部CDU准确率为79.03%,较其在甲状腺"冷结节"中判定的准确率无显著性差异(P>0.05);99mTc-TF显像准确率为91.94%,较其在甲状腺"冷结节"中,判定的准确率增高(P<0.05)。99mTc-TF显像判定准确率高于颈部CDU(P<0.05)。结论99mTc-TF显像在直径较大的甲状腺"冷结节"的性质判定准确率优于颈部CDU检查。Objective To identify the diagnosis value of ^99mTc-tetrofosmin imaging in thyroid ＂cold nodule＂ by comparing the diagnostic results of ^99mTc-tetrofosmin imaging and neck Color Doppler Ultrasonography （CDU）. Methods 60 patients with thyroid ＂cold nodule＂ determined by ^99mTcO4^- imaging were chosen. Regarded pathological result as the standard and compared diagnostic value of ^99mTc-tetrofosmin imaging and neck CDU in analyzing 96 thyroid ＂cold nodules＂ ,62 thyroid ＂cold nodules＂ with diameter greater than 1 cm respectively. Results There were 52 cases of benign,44 cases of malignancy in 96 thyroid ＂cold nodules＂. The accurate of neck CDU and ^99mTc-TF were 79. 17% and 77.08% respectively,there was no significant difference（P 〉0. 05）. There were 34 cases of benign, 28 cases of malignancy in 62 cases of thyroid ＂cold nodule＂ with diameter 〉 1cm. The accurate of neck CDU was 79.03% , there was no significant difference （ P 〉 0. 05 ） comparing that in thyroid ＂cold nodule＂. The accurate of ^99mTc-TF was 91.94%, higher than that in thyroid ＂cold nodule＂ （ P 〈 0.05 ） and that of neck CDU （P 〈 0. 05 ）. Conclusions ^99mTc-TF imaging is more sensitive in large diameter thyroid ＂cold nodule＂.

关 键 词：甲状腺 “冷结节” 核素显像 1 2-双〔双-(2-乙氧乙基)膦〕 

分 类 号：R455.5[医药卫生—运动医学]