便携式连续性血液净化机海上犬试验性能测试  

Performance measurement of the portable continuous blood purification machine in adult hybrid dogs at sea

作　　者：余永武[1] 周春华[1] 李洪艳[1] 董珍[1] 何萍[1] 温圆圆[1] 赵君[1] 

机构地区：[1]海军总医院肾脏病科,北京100048

出　　处：《中华航海医学与高气压医学杂志》2009年第5期305-307,共3页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

基　　金：海军后勤科研课题（07-3308）

摘　　要：目的验证海上环境下便携式连续性血液净化机（mobile continous blood purification machine，MCBPM）持续静-静脉血液滤过（continous veno—venous hemofihration，CVVHF）治疗的有效性和安全性。方法在海上行驶的舰船上对4只成年杂种犬行CVVHF治疗，观察便携式连续性血液净化机的工作性能，测量机器显示的每小时置换液量、废液量与实测值之间的误差，并观察治疗前后犬的生命体征、血常规及肾功能。结果（1）治疗中，犬的生命体征平稳；治疗后，犬的血常规、电解质无明显变化，血肌酐、尿素氮较治疗前下降；（2）治疗中，机器每小时置换液量机显值与实测值的误差为0．28％，废液的机显值与实测值的误差为0．17％，符合国家行业标准；机器运转正常，各项报警指标按设置值正常报警。结论MCBPM能在海上摇摆、颠簸、震动等情况下对犬进行CVVHF治疗，并且安全、有效。Objective To verify the efficiency and safety of continuous veno - venous hemofiltration （CVVHF） therapy by using the portable continuous blood purification machine （MCBPM） at sea. Methods Four adult hybrid dogs were administered with CVVHF at sea. Performance of MCBPM was closely observed for continuous running, the error in the amount of liquid displacement an hour and the amount of waste liquid between the machine - displayed value and the real - time value. Vital signs, blood routine and renal function of the dogs were also monitored both before and after treatment. Results （ 1 ） Vital sign of the dogs were stable during CVVHF therapy. No significant changes in blood routine and electrolyte were noted both before and after therapy. Serum creatinine and urea nitrogen decreased significantly when compared with those before therapy. （2） The error between the machine - displayed value and the real value in the quantity of displaced liquid was 0.28%, and the error for the waste liquid was 0.17%. The machine ran smoothly and alarms went off as set by the monitoring system. Conclusions CVVHF therapy could be successfully administered to the hybrid dogs by using MCBPM onboard the ship with safe and effective results.

关 键 词：便携式血液净化机 连续性血液净化 海上试验 犬 

分 类 号：TH7[机械工程—仪器科学与技术]