甘肃省部分人群甲、乙、丙和戊型肝炎感染的血清学调查  

Hepatitis viruses infection situation in human population of the Gansu province

作　　者：鲁健[1] 李红育[2] 田瑞光[1] 江永珍[1] 许亚宁[2] 于德山[2] 蒋建祥[2] 毕胜利[1] 

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,北京100052 [2]甘肃省疾病预防控制中心

出　　处：《中华实验和临床病毒学杂志》2009年第5期349-351,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的了解健康人群肝炎病毒感染现状。方法采用ELISA方法检测人群血清中抗甲（HAV-IgG）、乙（HBsAg和HBsAb）、丙（HCV．IgG）和戊型肝炎病毒抗体（HEV．IgG）。1977份人群血清收集于2008年5—10月。结果人群肝炎病毒抗体阳性率，HAV—IgG为84．57％（1672／1977），HBsAg和HBsAb为4．81％（95／1977）和28．73％（568／1977），HCV—IgG为0．46％（9／1977），HEV—IgG为13．10％（259／1977）。不同年龄段的人群肝炎病毒抗体阳性率分布，HAV—IgG阳性率，在≤9岁组至≥60岁组为43．21％-95．56％。HBsAg和HBsAb阳性率为2．09％-36．43％。HCV．IgG阳性总数9份，分布在30～59岁年龄组阳性为0．59％-1．79％。HEV-IgG阳性率，≤9岁组至≥3岁组分别为3．48％～21．67％。结论低年龄组人群HAV和HBsAb抗体明显低于人群总体水平，应及时加强免疫预防。HBsAg携带和HCV戚染下隆．HEV臆染晡年龄增长而升高．汉和同旗人群HEV感染室存存明显善别．Objective To investigate the seroprevalence of hepatitis viruses in human population of Gansu province. Methods ELISA was used for detecting anti-HAV IgG, HBsAg/HBsAb, anti-HCV IgG and anti-HEV IgG of the serum samples. All sample were collected in four areas of KL, LT, HN and ZhL of Gansu province in 2008. Results 1977 samples were detected, The positive rates of anti-HAV, HBsAg/HBsAb, anti-HCV, and anti- HEV are 84.57% （1672/1977）, 4.81% （95/1977）and 28.73% （568/1977）,0.46% （9/1977）, and 13.10% （259/1977）, respectively. The positive rate at different age group, for anti-HAV was 43.21% of ≤ 9 years old, 80.23%of 10-19 years old,93.02% of 20-29 years old, 95.55% of 30-39 years old, 95.60%-97.52% of 40-≥ 60 years old. For HBsAg/HBsAb were 2.09% or 29.27%, 3.02% or 21.81% ,6.20% or 36.43% ,5.93% or 31.16% ,6.43% or 31.43% ,7.32% or 24.88% ,3.33% or 28.89% at the same age group, respectively, for anti-HCV, was 0.59% of 30-39 years old, 1.79% of 40-49 years old, 0.98% of 50-59 years old. For HEV-IgG was 3.48% of ≤9 years old,6.05% of 10-19 years old, 8.53% of 20-29 years old,19.29%-21.67% of 30-≥ 60 years old. Conclusion The inoculation againt HAV and HBV is enhanced in the youngster population. HBsAg carrier and HCV infection is decreasing. The HEV infection in the Hui people is lower than the Han nationality.

关 键 词：肝炎病毒 抗体 病毒 血清学 

分 类 号：R181.3[医药卫生—流行病学]