穴位埋线治疗更年期综合征及其对性腺激素、β-内啡肽的影响  

Effect of catgut implantation at acupoint on gonadal hormone and β-endorphin in patients of climacteric syndrome

作　　者：李月梅[1] 庄礼兴[2] 张东淑[3] 罗一峰[3] 

机构地区：[1]广州中医药大学第一附属医院针灸科,广东广州510405 [2]广州中医药大学 [3]南方医院

出　　处：《中国针灸》2009年第11期865-867,共3页Chinese Acupuncture & Moxibustion

基　　金：广东省中医药管理局课题资助项目:1060093

摘　　要：目的:探索穴位埋线治疗更年期综合征的临床疗效及其机制。方法:将60例患者随机分为埋线组和西药组,每组30例。埋线组选取肾俞、子宫、三阴交进行穴位埋线治疗,西药组每天口服己烯雌酚片,观察比较两组的临床疗效及其对患者血清促卵泡生成激素(FSH)、促黄体生成激素(LH)、雌二醇(E2)及β-内啡肽的影响。结果:埋线组总有效率为93.3%,西药组总有效率为70.0%,埋线组优于西药组(P<0.05);埋线组β-内啡肽较治疗前明显上升;同时FSH降低,E2水平升高,与西药组比较差异均有统计学意义(P<0.05,P<0.01)。结论:穴位埋线治疗更年期综合征疗效显著,可明显改善患者卵巢功能,对内源性阿片肽类递质具有良性调整作用。Objective To explore the clinical therapeutic effect of catgut implantation at acupoint on climacteric syndrome （CS） and its mechanism. Methods Sixty cases were randomly divided into a catgut implantation group and a western medicine group, 30 cases in each group. The catgut implantation group was treated by catgut implantation at Shenshu （BL23）, Zigong （EX-CA1）, Sanyinjiao （SP 6）. The western medicine group was treated by oral administration of Dietbylstilbestrol tablet. Their therapeutic effects and changes of content of follicle-stimulating hormone （FSH）, luteotrophic hormone （LH）, estradiol （E2） and β-endorphin （β-EP） in serum were observed. Results The total effective rate was 93.3% in the catgut implantation group and 70.0% in the western medicine group with a significant difference between the two groups （P〈0.05）. After treatment, the β-EP concentration in the catgutation implant group was significantly increased （P〈0.05）, the FSH concentration was significantly reduced and E2 concentration was significantly increased as compared with those in the western medicine group （P〈0.05, P〈0.01）. Conclusion Catgut implantation at acupoint has an obvious therapeutic effects on CS. It can significantly improve the ovaries function and has a favorable regulative action on the endogenous opioid peptides.

关 键 词：埋线 更年期综合征 Β-内啡肽 性腺激素类 

分 类 号：R246.3[医药卫生—针灸推拿学]