有氧训练及热应激对运动大鼠肾脏组织NO、NOS及自由基代谢的影响  

Effects of Aerobic Endurance Training and Heat Stress on NO、NOS and Free Radical Metabolism in Kidney of Mice

作　　者：季丽萍[1] 陈惠宇[2] 

机构地区：[1]徐州师范大学体育学院,江苏徐州221116 [2]山东省菏泽学院体育系,山东菏泽274015

出　　处：《福建体育科技》2009年第5期34-37,共4页Fujian Sports Science and Technology

基　　金：江苏省高校自然科学基础研究项目(项目编号:08KJB340001)

摘　　要：目的:探讨有氧耐力训练对运动热应激大鼠肾脏组织NO、NOS及自由基代谢的影响。方法:对大鼠进行为期6w的递增负荷运动训练,并在运动末次施加热应激,测定大鼠肾脏组织NO、NOS、MDA和SOD含量或活性。结果:(1)运动加热应激使大鼠肾脏组织NO、NOS、iNOS和MDA显著高于安静组和急性运动组,SOD和SOD/MDA显著低于安静组和急性运动组;(2)训练安静组与安静对照组相比,MDA均显著下降,NO、NOS均显著上升;(3)训练后运动热应激大鼠肾脏组织NO、NOS、iNOS、MDA显著下降,SOD显著上升。结论:(1)在热环境下运动,机体NO、NOS和自由基代谢增加,抗氧化酶活性下降;(2)在常温下进行有氧耐力训练,可以适当提高机体的耐热性,降低运动热应激对机体的损伤。Objective ： Explore the effects of aerobic endurance training on NO, NOS and free radical metabolism in kidney of mice after exercise plus heat stress. Methods ： Mice were trained on treadmill for six weeks with incremental exercise and were exerted on heat stress in the last training. Results ： （ 1 ） After exercise plus heat stress, NO content and NOS and iNOS and MDA activity were increased more than those of the control group and exercise group. SOD and SOD/MDA were decreased less than those of the control group and exercise group. （ 2 ） MDA content of exercise train group was decreased than that of the control group. NO and NOS were increased remarkably. （ 3 ） After aerobic endurance training NO and NOS and iNOS and MDA in kidney of mice after exercise plus heat stress were decreased remarkably, SOD was increased remarkably. Conclusions ： （ 1 ） Heat stress exercise for long time, NO, NOS and free radical metabolism increases and anti - oxidase activity decreases; （ 2） Exercise with moderate intensity aerobic endurance under normal temperature could improve the endurance of heat stress and decrease body damage.

关 键 词：有氧耐力训练 运动热应激 肾脏 一氧化氮 一氧化氮合酶 自由基 

分 类 号：G804.6[文化科学—运动人体科学]