皖北农村地区AIDS病人抗病毒治疗依从性及相关因素研究  

STUDY ON COMPLIANCE AND RELATED FACTORS OF RECEIVING ANTIRETROVIRAL TREATMENT AMONG ACQUIRED IMMUNE DEFICIENCY SYNDROME PATIENTS IN THE NORTHERN RURAL AREA OF ANHUI

作　　者：于玉领[1] 张秀军[1] 沈琼[1] 孙业桓[1] 

机构地区：[1]安徽医科大学公共卫生学院流行病学与卫生统计学系

出　　处：《现代预防医学》2009年第22期4201-4203,4214,共4页Modern Preventive Medicine

基　　金：全球基金第三轮艾滋病项目(NGO2005023;NGO2007057)

摘　　要：[目的]了解皖北农村地区获得性免疫综合征(AIDS)病人抗病毒治疗依从性现状及其相关因素。[方法]整群抽取皖北3县(临泉、界首、萧县)农村地区正在服用抗病毒药物的AIDS病人,通过入户的方式进行询问调查和现场观察。[结果]研究发现,农村地区AIDS病人抗病毒治疗的服药依从性低于90%的有21人,占15.1%,调查时服用人数最多的药物为司他夫定(Stavudine),药物依从性最好的为茚地那韦(indinavir)。服药者中有35人因为忘记而出现间断性停药,占85.4%。多因素Logistic分析显示,服药者身体越差服药依从性越好,而督导医生的水平差、服药者经常出现希望自己死了才好的念头则服药依从性差。[结论]该地区AIDS病人抗病毒治疗服药依从性不高,并受多种因素影响,应大力开展有针对性的健康教育及抗病毒治疗前的服药依从性教育。[Objective] To study on the compliance status and related factors of receiving antiretroviral treatment（ART） among AIDS patients in the northern rural area of Anhui province.[Methods] AIDS patients taking the antiviral drugs from three cities in northern rural areas of Anhui（Liquan,jieshou and Xiaoxian） were sampled by using cluster sampling.Investigation and field observation were conducted by in-door investigation.[Results] The compliance rates of 21 AIDS patients were below 90%,accounted for 15.1%.Stavudine was the most common drug for antiviral treatment,and the highest compliance of drug was Indinavir.There were 35 people did not take drugs due to forgeting,accounted for 85.4%.Multivariate Logistic regression analysis showed that the worse of people＇s body was,the better of compliance was,but the worse of supervise doctor＇s level and people who always want to dead showed,the worse of compliance was.[Conclusion] The compliance of receiving anti-retroviral therapy among AIDS patients was not high,and was influenced by various factors.We should carry out the targeted health education and the compliance education of anti-viral treatment before treatment.

关 键 词：农村 AIDS 抗病毒治疗 依从性 相关因素 

分 类 号：R512.91[医药卫生—内科学]