临床假丝酵母感染的检测及流行病学分析  

EPIDEMIOLOGIAL ANALYSIS and CLINICAL DETECTION OF CANDIDAL INFECTION

作　　者：孙晓红[1,2] 贺丹[1] 张艳华[1] 李涵[1] 田庄[1] 王丽[1] 

机构地区：[1]吉林大学白求恩医学院病原生物学系,长春130021 [2]北华大学医学检验学院

出　　处：《现代预防医学》2009年第22期4303-4304,共2页Modern Preventive Medicine

基　　金：国家自然科学基金重大国际合作资助项目(30910103903);吉林省科技发展计划重点资助项目(20080444-2)

摘　　要：[目的]探讨医院内真菌感染现状及流行病学特征,为临床真菌感染的预防和治疗提供理论依据。[方法]收集临床真菌感染患者标本,进行分离、鉴定。并从患者年龄、标本来源、病原菌种类、科室分布等方面进行流行病学分析。[结果]收集临床假丝酵母感染标本209例。主要来源于呼吸内科(61.2%),以痰标本的真菌分离率最高(82.8%)。分离出的病原菌以白假丝酵母所占比例最高(72.2%),依次为热带假丝酵母(12.5%)、光滑假丝酵母(8.6%)、克柔假丝酵母(2.4%)、其他假丝酵母(4.3%)。60岁以上老年患者占真菌感染人数的83.7%。[结论]应高度重视医院内真菌感染,加强易受侵袭性真菌感染患者的病原学监测,对真菌感染的高危人群应进行积极的预防。[Objective] To investigate the current condition and epidemiological factors of clinical fungal infection in hospital,and provide a theoretical proof for controlling fungal infection.[Methods] We collected specimens of clinical fungal infection,and identified the isolates,then performed epidemiologic analysis for cases according to the age of patients,source of samples,species and division distribution.[Results] 209 strains of Candida were collected.The sources of infection were mainly come from respiratory system（61.2%）.The highest positive rate of sputum specimen of fungal infection was 82.8%.The infection rate of Candida albicans was as high as 72.2%,followed by Candida tropicalis（12.5%）,Candida glabrata（8.6%）,Candida krusei（2.4%） and others（4.3%）.The patients above the age of 60 years old had the highest infection rate（83.7%）.[Conclusion] We should pay much attention to the fungal infection in hospital,actively monitoring pathogens to patients vulnerable to invasive fungal infection and specially prevent the high risk group.

关 键 词：病原真菌 真菌感染 流行病学 

分 类 号：R181.22[医药卫生—流行病学]