植入式开路型脉冲缓释双路人工胰(泵)的设计及实验研究  

Design and Experimental Study of an Opening Type Implantable Artificial Pancreas Equipped with a Pulse Pump and a Micropore Slow Delivery Pump

作　　者：王建[1] 陈槐卿[2] 张荣荣[1] 祝玉兰[1] 

机构地区：[1]四川省肿瘤医院,成都610041 [2]华西医科大学基础医学院,成都610041

出　　处：《生物医学工程学杂志》1998年第4期340-343,共4页Journal of Biomedical Engineering

摘　　要：依据正常人体自身分泌胰岛素的生理特点，提出要用脉冲、缓释双路供释胰岛素的设计思路，分别模拟胰岛素的分泌的截然不同的两种方式。并通过体外试验，建立了类似餐后的大量、迅速的脉冲分泌方式和２４ｈ持续、稳定的微量分泌方式这两种模型。本文的结果为今后进一步研制植入式开路型人工胰（泵）奠定了理论基础。According to physiologic character of insulin secretion of normal body, one new design has been advanced. It can provide insulin with both pulsed and slow released ways, and imitate seperately two completely different forms of insulin secretion. Through extracorpored experiment, one parallel model has been set up. One function is similar to post cibum largely and quickly pulsed insulin secretion, other one is continuous and stable micro secretion in 24 hours. The theoretical base for researching furtherly the open implanted artificial pancreas (pump) dependls on the result of this article.

关 键 词：脉冲泵 微孔缓释泵 糖尿病 人工胰 

分 类 号：R587.105[医药卫生—内分泌] R318.15[医药卫生—内科学]