脑溢安颗粒剂对脑出血病人的血液流变学与RCD的影响  

Effects of Nao Yi an granule on hemorheological indexes and RCD in patients with hemorrhagic stroke

作　　者：梁清华 黎杏群 张花先 

出　　处：《湖南医科大学学报》1998年第6期545-548,共4页Bulletin of Hunan Medical University

摘　　要：对４０例脑出血患者采用脑溢安颗粒剂（中药组）和西药（西药组）治疗，观察血液流变学与红细胞变形能力（ＲＣＤ）的变化。结果表明：两组治疗前全血比粘度的高切、低切；全血还原粘度的高切；血浆比粘度以及ＲＣＤ均较正常人对照组高（均Ｐ＜０．０１）。治疗后，中药组上述指标均较治疗前明显降低（Ｐ＜０．０１）；而西药组较治前稍有降低，无统计学意义（Ｐ＞０．０５）；且中药组明显低于西药组（Ｐ＜０．０１）。提示中药脑溢安颗粒剂对降低血液粘度，提高ＲＣＤ，改善脑组织血液灌流，防止脑组织缺血缺氧继发性损伤，保护脑组织。The effects of Nao Yi an granule(Chinese medicine group, CMG) and western medicine(western medicine group, WMG) on hemorheological indexes and red cell deformability(RCD) were investigated in 40 patients with hemorrhagic stroke. The results showed that whole blood relative viscosity(high and low shear), whole blood reduced viscosity(high shear), plasm relative viscosity and RCD were significantly elevated before the treatment in both group than those of the control group(P<0.01). After the treatment, the above indexes were lower in CMG than before the treatment and also lower in CMG than in WMG(P<0.01). It is indicated that the Nao Yi an granule is obviously superior to western medicine on the decrease of blood viscosity, increase of RCD, improvement of blood perfusion of brain tissue, protection of brain tissue and improved clinical in patients with hemorrhagic stroke.

关 键 词：脑出血 血液流变学 脑溢安 RCD 中医药疗法 

分 类 号：R277.733.4[医药卫生—中医学] R331.1