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机构地区:[1]佛山市南方医科大学附属南海医院妇产科,广东佛山528200
出 处:《临床和实验医学杂志》2009年第11期38-39,共2页Journal of Clinical and Experimental Medicine
摘 要:目的探讨异丙酚静脉麻醉下行人工流产手术的临床效果。方法选择自愿要求终止妊娠的早孕妇女,分异丙酚组300例、利多卡因组300例及对照组200例进行对比分析。结果异丙酚组用药后收缩压(SBP)、舒张压(DBP)、心率(HR)、呼吸(R)、血氧饱和度(SpO2)等指标较用药前均呈下降趋势,但差异无显著性(P>0.05)。异丙酚组镇痛有效率为100%,显著高于利多卡因组(69.67%)和对照组(26.00%),3组的镇痛有效率比较,差异有显著性(P<0.01)。异丙酚组无1例人工流产综合征发生,而利多卡因组发生率为4.67%,对照组为34.50%,3组比较差异有显著性(P<0.01)。3组在出血量上差异无显著性(P>0.05)。结论异丙酚静脉麻醉用于人工流产术镇痛效果明显,可降低人工流产综合征的发生率,且无明显呼吸抑制作用,不增加出血量,值得临床推广应用。Objective To observe the clinic effect of venous anesthesia with propofol for induced abortion.Methods Eight hundred early pregnant women demanded for induced abortion were divided into 3 groups:propofol group(300 cases),lidocaine group(300 cases)and control group(200 cases).Results The parameters as SBP,DBP,HR,R and SPO2 were descended after application of propofol,but their differences were not significant(P0.05).The efficient analgesia in propofol group(100%)was significantly better than that of lidocaine(69.67%)and control(26.00%)groups,and their differences were significant(P0.01).Induced abortion syndrome was not seen in cases of propofol group,its incidence rates in cases of lidocaine and control group were 4.67% and 34.50% respectively,and their differences were significant(P0.01).The difference of hemorrhage among these 3 groups was not significant(P0.05).Conclusion Propofol is good for indolent induced abortion with advantages of good analgesic effect,low incidence of induced abortion syndrome and less respiratory depression and hemorrhage.
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