美托洛尔治疗血管迷走性晕厥的疗效探讨  

Effect of metoprolol in prevention for vasovagal syncope

作　　者：文俐[1] 罗开良[1] 薛宁 钱元菊 

机构地区：[1]重庆医科大学第二临床学院心内科

出　　处：《重庆医科大学学报》1998年第4期416-418,共3页Journal of Chongqing Medical University

摘　　要：采用倾斜试验对57例血管迷走性晕厥患者进仔了研究,28例阳性者被随机分为美托洛尔治疗组和安慰剂对照组。用药7天后重复倾斜试验来评价药物的短期疗效,临床随访有无症状的再次发作来评价药物的长期疗效。结果:治疗7天后重复倾斜试验阴性,在治疗组为82%(9/11例),对照组为88%(8/9例)。P>0.05;治疗组临床随访平均132天,对照组平均174天,两组各有2例(14%)有症状再发。Fifty-seven consecutive Patients with Vasovagal Syncope(VVS)underwent 60 degree tilt table test(TTT).- Twenty-eight patients with a positive result of TTT were divided into metoprolol group and placebo group,randomly.The short-term therapeutic effect was assessed by repeated TTT on the 7th day after treatment and the long-term effect by clinical follow-up.Results The negative rate of repeated TTT was 82%(9/11)in metoprolol grorp compared with 88%(8/9)in control group(P>0.05).The clinical follow-up period of metoprolol group averaged 132 days and the control group 174 days.Two cases in both groups,respectively,had recurrence of syncope or presyncope.The specific effect of metoprolol is not found in our study.

关 键 词：晕厥 美托洛尔 血管迷走性 药物疗法 

分 类 号：R544.204[医药卫生—心血管疾病]