荔枝草的化学成分  

Chemical constituents of the whole herbs of Salvia plebeia R. Br.

作　　者：韩国华[1] 李占林[1] 孙琳[1] 华会明[1] 

机构地区：[1]沈阳药科大学中药学院,辽宁沈阳110016

出　　处：《沈阳药科大学学报》2009年第11期896-899,共4页Journal of Shenyang Pharmaceutical University

摘　　要：目的对荔枝草(Salvia plebeiaR Br.)全草体积分数为70%的乙醇溶液溶液提取物的化学成分进行研究。方法利用制备薄层色谱、反复硅胶、Sephadex LH-20和开放ODS柱色谱等方法进行分离纯化;根据理化性质及波谱分析对分离得到的化合物进行结构研究。结果分离得到9个化合物,分别鉴定为β-谷甾醇(β-sitosterol,1)、高车前素(hispidulin,2)、鼠尾草酚(carnosol,3)、rosmadi-al(4)、熊果酸(ursolic acid,5)、柳穿鱼黄素(pectolinarigenin,6)、表迷迭香酚(epirosmanol,7)、咖啡酸甲酯(caffeic acid methyl ester,8)、东莨菪素(scopoletin,9)。结论化合物8、9为首次从该属植物中分离得到,化合物3-7为首次从该植物中分离得到。Objective To study the chemical constituents of whole plant of Salvia plebeia R. Br. Methods Compounds were isolated and purified repeatedly by preparative TLC and silica gel, Sephadex LH-20, and ODS column chromatography, and their chemical structures were elucidated by their physico-chemical properties and spectral analysis. Results Nine compounds were obtained and identified as β-sitosterol （1）, hispidulin （2）, carnosol （ 3 ）, rosmadial （ 4 ）, ursolic acid （ 5 ）, pectolinarigenin （ 6 ）, epirosmanol （ 7 ）, caffeic acid methyl ester（8）, and scopoletin （9）. Conclusions Compounds 8 and 9 are obtained from Salvia genus for the f＇n-st time, and compounds 3-7 are reported from this plant for the first time.

关 键 词：荔枝草 化学成分 二萜 结构鉴定 

分 类 号：R284[医药卫生—中药学]