从丙基硫氧嘧啶不良反应的识别与干预谈药师的临床药学实践  

Clinical pharmacy practice by means of identification and intervention of adverse reactions of propylthiouracil

作　　者：刘敏[1,2] 李忠东[2] 邵宏[1] 

机构地区：[1]北京大学药学院药事管理与临床药学系,北京100191 [2]空军总医院药学部,北京100142

出　　处：《中国新药杂志》2009年第22期2189-2192,共4页Chinese Journal of New Drugs

摘　　要：目的:通过药师识别丙基硫氧嘧啶不良反应的过程阐述药师进行临床药学实践的切入点。方法:通过信息检索收集丙基硫氧嘧啶不良反应561例,经统计发现丙基硫氧嘧啶不良反应的普遍规律,再分析实际案例,最终识别出丙基硫氧嘧啶的不良反应,以此进行临床用药干预。结果:以药物信息学为基础,能全面了解丙基硫氧嘧啶的不良反应机制与表现,开展有效的临床药学实践。结论:药师通过信息学调查和案例分析,以识别药物不良反应为切入点的临床药学实践模式值得推广。objective：To figure out a breakthrough point for pharmacists to develop clinical pharmacy practice by means of identification of adverse reactions of propylthiouracil.Methods：The cases（n=561） of adverse reactions of propylthiouracil were collected in literature,and their popular regularity was disinterred.The adverse reactions of propylthiouracil were identified from clinical medication cases and intervened by pharmacists.Results：On the basis of drug informatics,the adverse reactions of propylthiouracil were fully understood and efficiently used in clinical pharmacy practice. Conclusion：The mode of clinical pharmacy practice introduced by the identification of adverse drug reactions as a breakthrough point is worth of commendation.

关 键 词：丙基硫氧嘧啶 药物不良反应 信息检索 药师 临床药学实践 

分 类 号：R95[医药卫生—药学]