骨骼肌细胞凋亡的影响因素:低氧训练效应  

Hypoxic training effects on apoptosis of skeletal muscle cells

作　　者：刘铭[1] 瞿树林[1] 

机构地区：[1]湖南师范大学体育学院,湖南省长沙市410012

出　　处：《中国组织工程研究与临床康复》2009年第41期8139-8142,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：湖南省自然科学基金项目(05JJ30066)~~

摘　　要：在外界低氧环境的刺激下,骨骼肌细胞易处于缺氧状态,这种缺氧趋势与细胞凋亡存在着某种直接或者间接的联系。在一定强度的运动中,机体的组织和细胞处于一种相对缺血和缺氧的状态,肌肉细胞内氧分压降到很低水平时,在骨骼肌组织中也能检测到细胞凋亡的发生。但有关低氧训练对骨骼肌细胞凋亡的影响目前尚未见报道,低氧训练对骨骼肌细胞凋亡会产生何种影响,骨骼肌细胞凋亡与不同低氧训练刺激时间和方式的关系如何,有必要进行深入研究和探讨。Under the stimulus of hypoxic environment, skeletal muscle cells are prone to present with anoxia. This hypoxic situation directly or indirectly associates with apoptosis. In a certain intensity exercise, tissues and cells are apt to relative ischemia and hypoxia. When oxygen partial pressure descends to a low level, apoptosis can be measured in skeletal muscles. At the present time, the research between hypoxic training and apoptosis in skeletal muscles has not been reported, which needs to study and discuss hypoxia training effect on apoptosis in skeletal muscles, further the relationship of apoptosis in skeletal muscles and different hypoxic mode and time.

关 键 词：低氧训练 骨骼肌 自由基 基因表达 细胞凋亡 

分 类 号：R318[医药卫生—生物医学工程]