西安、天津、广州3城市膝骨性关节炎患者、门诊就治者及社区人员膝骨关节炎主要致病因素:多中心整群抽样分层调查  

Main pathogenic factors in knee osteoarthritis patients, outpatients and community staff from Xi’ an, Tianjin and Guangzhou: Multicenter cluster sampling epidemiological survey

作　　者：王宇强 王小华 刘天盛 浮煜[2] 林洁[3] 刘德玉[3] 

机构地区：[1]武装警察部队医学院附属医院,天津市300162 [2]西安交通大学附属一医院,陕西省西安市710061 [3]陕西中医学院,陕西省咸阳市712083

出　　处：《中国组织工程研究与临床康复》2009年第41期8155-8159,共5页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:通过流行病学调查,了解膝关节骨性关节炎主要致病因素并进行相关性分析。方法:受试者来自2003/2007西安、天津、广州市3城市,包括2组住院患者,4组门诊患者,1组社区人员,共计964人。采用问卷调查方式从3个观察点对7组人群进行调查,用VF建立数据库,分析社会人口学特征,进行3地差异性比较。分析体质量指数与性别、职业、年龄的关系,发病部位、生活质量分别与性别、职业、年龄、体质量的关系,职业与发病年龄关系。进行膝关节骨性关节炎的Logistic的非条件回归分析。结果:①女性膝关节骨性关节炎多于男性。②职业人群发病家务较多,科教文卫最少。③工人发病体质量指数值较小,体质量指数值和年龄呈正相关,50岁以上人群体质量指数值明显偏大。④发病部位与性别、职业、年龄、体质量指数无相关性。⑤发病年龄以工人较早,家务较晚。⑥生活质量良性人群占调查人群比例最大,但对于膝骨关节炎发病还不能说有相关性。结论:膝关节骨性关节炎发病与性别、年龄、体质量指数、职业(工人、家务)相关,其中年龄危险度最高,其次是性别、体质量指数、职业。生活质量对于膝骨关节炎致病没有危险性。OBJECTIVE： To understand the key pathogenic factors in knee osteoarthritis through epidemiology survey and to conduct a correlation analysis. METHODS： A total of 964 subjects were recruited from Xi＇an, Tianjin and Guangzhou between 2003 and 2007, including two groups inpatients, four groups outpatients, and one group community people. They were investigated with questionnaire investigation method. By use of VF5.0, a database was built to analyze social demographical characteristics among three cities and to investigate the correlation of body mass index （BMI） with gender, occupation, age, the correlation between affected site, life quality and gender, occupation, age and BMI, and the correlation between occupation and affected age. An unconditional Logistic regression analysis was conducted. RESULTS：①Female was shown to be more susceptible than male. ②The people of HOUSEWORK were more than those of SCIENCE, EDUCATION and HYGIENE.③The worker＇s BMI was the lowest, and BMI had a positive correlation with age. BMI was significantly higher in the people at more than 50 years old. ④The affected site had no correlation with gender, occupation age and BMI. ⑤During the people of high susceptibility to knee osteoarthritis, the WORKER was early and HOUSEWORK was late. ⑥The people exhibiting good life quality had the greatest proportion of all surveyed people, but life quality was not correlated with knee osteoarthritis. CONCLUSION： Gender, age, BMI and occupation （housework, worker） are the main pathogenic factors of knee osteoarthritis. Among them, age has the greatest risk, and then gender, BMI and occupation. Life quality has no risk of pathogenesis of knee osteoarthdtis.

关 键 词：膝关节骨性关节炎 流行病学 致病因素 

分 类 号：R681[医药卫生—骨科学]